Linked Life Data

1992299

Source:http://linkedlifedata.com/resource/pubmed/id/1992299

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1
pubmed:dateCreated
1991-3-8
pubmed:abstractText
The aim of this study was to investigate the contractile protein characteristics after 5-day (Cosmos 1514) and 7-day (Cosmos 1667) spaceflights. The experiments were performed on skinned fibers from the soleus, gastrocnemius lateralis, and plantaris muscles isolated from Wistar rats. A reduction in fiber diameter might explain the decrease in the maximal tension in the soleus, whereas this tension was unaltered in the gastrocnemius and the plantaris. Moreover the calcium sensitivity of the myofilament appeared modified in the soleus and in the gastrocnemius: The tension/pCa relationships were shifted toward higher calcium concentrations, indicating a decrease in the apparent calcium binding constant of the troponin C. The tension/pCa relationship appeared unaltered in the plantaris after spaceflight. Finally, the studies of the time to reach a steady tension indicated an increase in the rate of force development in the soleus and, on the contrary, a slowing down in the plantaris. No change in the gastrocnemius was found. The results were analyzed with references to the different muscle functions in disuse atrophy.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Jan
pubmed:issn
0148-639X
pubmed:author
pubmed:issnType
Print
pubmed:volume
14
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
70-8
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1991
pubmed:articleTitle
Effects of short spaceflights on mechanical characteristics of rat muscles.
pubmed:affiliation
Laboratoire de Physiologie des Structures Contractiles, Université des Sciences et Techniques de Lille, Villeneuve d'Ascq, France.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't