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rdf:type |
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lifeskim:mentions |
umls-concept:C0006141,
umls-concept:C0010453,
umls-concept:C0014609,
umls-concept:C0086418,
umls-concept:C0205431,
umls-concept:C0439858,
umls-concept:C0450363,
umls-concept:C0596963,
umls-concept:C0682578,
umls-concept:C1521761,
umls-concept:C1707959
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pubmed:dateCreated |
2009-11-27
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pubmed:abstractText |
Basoapical polarity in epithelia is critical for proper tissue function, and control of proliferation and survival. Cell culture models that recapitulate epithelial tissue architecture are invaluable to unravel developmental and disease mechanisms. Although factors important for the establishment of basal polarity have been identified, requirements for the formation of apical polarity in three-dimensional tissue structures have not been thoroughly investigated.
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pubmed:grant |
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pubmed:commentsCorrections |
http://linkedlifedata.com/resource/pubmed/commentcorrection/19917093-10705920,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19917093-10780659,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19917093-11790345,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19917093-11801722,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19917093-12242153,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19917093-12526790,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19917093-12798140,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19917093-12808020,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19917093-1384042,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19917093-14998921,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19917093-15242767,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19917093-15878367,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19917093-15976445,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19917093-16169468,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19917093-16280548,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19917093-16607610,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19917093-17396127,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19917093-17405811,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19917093-18089605,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19917093-18333775,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19917093-18388309,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19917093-18419529,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19917093-18983815,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19917093-1928301,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19917093-19412339,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19917093-1975513,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19917093-3558253,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19917093-6217835,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19917093-7544798,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19917093-7760750,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19917093-8071986,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19917093-9105051,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19917093-9458363,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19917093-9843954,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19917093-9843973
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:issn |
1741-7007
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pubmed:author |
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pubmed:issnType |
Electronic
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pubmed:volume |
7
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
77
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pubmed:dateRevised |
2010-9-28
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pubmed:meshHeading |
pubmed-meshheading:19917093-Basement Membrane,
pubmed-meshheading:19917093-Breast,
pubmed-meshheading:19917093-Cell Culture Techniques,
pubmed-meshheading:19917093-Cell Differentiation,
pubmed-meshheading:19917093-Cell Line,
pubmed-meshheading:19917093-Cell Polarity,
pubmed-meshheading:19917093-Collagen Type IV,
pubmed-meshheading:19917093-Epithelial Cells,
pubmed-meshheading:19917093-Female,
pubmed-meshheading:19917093-High-Throughput Screening Assays,
pubmed-meshheading:19917093-Humans,
pubmed-meshheading:19917093-Mammary Glands, Human,
pubmed-meshheading:19917093-Signal Transduction,
pubmed-meshheading:19917093-Spheroids, Cellular
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pubmed:year |
2009
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pubmed:articleTitle |
Factors necessary to produce basoapical polarity in human glandular epithelium formed in conventional and high-throughput three-dimensional culture: example of the breast epithelium.
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pubmed:affiliation |
Department of Basic Medical Sciences and Purdue Center for Cancer Research, Purdue University, West Lafayette, IN 47907, USA. cplachot@luminexcorp.com
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't,
Research Support, N.I.H., Extramural
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