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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
6
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pubmed:dateCreated |
2010-11-15
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pubmed:abstractText |
CD40 and CD40L, as costimulatory molecules, are reported to play a critical role for cytokine production and antigen-specific T-cell activation in acute viral myocarditis (VMC). The purpose of this study was to probe the therapeutic effect of CD40-Ig in coxsackievirus B3 (CVB3)-induced myocarditis.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/Antigens, CD40,
http://linkedlifedata.com/resource/pubmed/chemical/CD40 Ligand,
http://linkedlifedata.com/resource/pubmed/chemical/CD40Ig protein, recombinant,
http://linkedlifedata.com/resource/pubmed/chemical/Interferon-gamma,
http://linkedlifedata.com/resource/pubmed/chemical/Interleukin-4,
http://linkedlifedata.com/resource/pubmed/chemical/RNA, Messenger,
http://linkedlifedata.com/resource/pubmed/chemical/RNA, Viral,
http://linkedlifedata.com/resource/pubmed/chemical/Recombinant Fusion Proteins
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pubmed:status |
MEDLINE
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pubmed:issn |
1879-1336
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pubmed:author |
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pubmed:copyrightInfo |
Copyright © 2010 Elsevier Inc. All rights reserved.
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pubmed:issnType |
Electronic
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pubmed:volume |
19
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
371-6
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pubmed:meshHeading |
pubmed-meshheading:19914091-Animals,
pubmed-meshheading:19914091-Antigens, CD40,
pubmed-meshheading:19914091-CD40 Ligand,
pubmed-meshheading:19914091-Coxsackievirus Infections,
pubmed-meshheading:19914091-Disease Models, Animal,
pubmed-meshheading:19914091-Disease Progression,
pubmed-meshheading:19914091-Enterovirus B, Human,
pubmed-meshheading:19914091-Immunohistochemistry,
pubmed-meshheading:19914091-Interferon-gamma,
pubmed-meshheading:19914091-Interleukin-4,
pubmed-meshheading:19914091-Male,
pubmed-meshheading:19914091-Mice,
pubmed-meshheading:19914091-Mice, Inbred BALB C,
pubmed-meshheading:19914091-Myocarditis,
pubmed-meshheading:19914091-Myocardium,
pubmed-meshheading:19914091-RNA, Messenger,
pubmed-meshheading:19914091-RNA, Viral,
pubmed-meshheading:19914091-Recombinant Fusion Proteins,
pubmed-meshheading:19914091-Reverse Transcriptase Polymerase Chain Reaction,
pubmed-meshheading:19914091-Th1 Cells,
pubmed-meshheading:19914091-Th2 Cells,
pubmed-meshheading:19914091-Time Factors,
pubmed-meshheading:19914091-Virus Replication
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pubmed:articleTitle |
Blocking the CD40-CD40L interaction by CD40-Ig reduces disease progress in murine myocarditis induced by CVB3.
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pubmed:affiliation |
Division of Cardiology, Department of Pediatrics, Provincial Hospital Affiliated to Shandong University, Jinan, Shandong, PR China. hanbo35@163.com
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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