Source:http://linkedlifedata.com/resource/pubmed/id/19912363
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
5
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pubmed:dateCreated |
2009-11-16
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pubmed:abstractText |
The chemokine receptor CXCR4 plays a prominent role in the biology of many different tumours, promoting angiogenesis and metastasis. The impact of CXCR4 expression on tumour biology has been described in various gastrointestinal malignancies, but data on its in situ expression and clinicopathological correlations are sparse. Using a novel specific rabbit anti-CXCR4 antibody, the aim was to assess CXCR4 expression immunohistochemically on tissue microarrays generated from 402 colorectal cancers (CRCs) and compare it with CXCL12 expression and various clinicopathological parameters.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Nov
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pubmed:issn |
1365-2559
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pubmed:author | |
pubmed:issnType |
Electronic
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pubmed:volume |
55
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
576-86
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pubmed:dateRevised |
2010-11-18
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pubmed:meshHeading |
pubmed-meshheading:19912363-Aged,
pubmed-meshheading:19912363-Animals,
pubmed-meshheading:19912363-Chemokine CXCL12,
pubmed-meshheading:19912363-Colorectal Neoplasms,
pubmed-meshheading:19912363-Female,
pubmed-meshheading:19912363-Humans,
pubmed-meshheading:19912363-Immunohistochemistry,
pubmed-meshheading:19912363-Kaplan-Meier Estimate,
pubmed-meshheading:19912363-Middle Aged,
pubmed-meshheading:19912363-Neoplasm Staging,
pubmed-meshheading:19912363-Neovascularization, Pathologic,
pubmed-meshheading:19912363-Prognosis,
pubmed-meshheading:19912363-Receptors, CXCR4,
pubmed-meshheading:19912363-Tissue Array Analysis,
pubmed-meshheading:19912363-Tumor Markers, Biological
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pubmed:year |
2009
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pubmed:articleTitle |
The role of vascular CXCR4 expression in colorectal carcinoma.
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pubmed:affiliation |
Institute of Pathology Campus Mitte, Charité University Hospital, Berlin, Germany. barbara.ingold-heppner@charite.de
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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