Linked Life Data

19908798

Source:http://linkedlifedata.com/resource/pubmed/id/19908798

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
12
pubmed:dateCreated
2009-11-13
pubmed:abstractText
Lap-on-a-chip system is one of challenging parts in nano and bio engineering fields, for instance, microfluidic channels on the chip are useful for selecting a target particle and mass transferring of boiomolecules in fluid. However, since experimental approach is highly expensive both in time and cost, alternative reliable methods are required to conceive optimized channels. The purpose of this research is to simulate a nanoparticle focusing lens in a microfluidic channel from nanoparticle control point of view. A promising immersed finite element method is expanded to estimate the path of randomly moving nanoparticles through a focusing lens. The channel flow is assumed as incompressible viscous fluid and Brownian motion effects as well as initial position of particle are quantitatively examined. As a representative result, while the nanoparticles with/without Brownian motion were focused along the center of the channel, the concentration factor representing focusing efficiency was calculated. Therefore, it is expected that the newly proposed numerical method considering Brownian motion will be efficiently applicable to design the microfluidic channel containing various particles, molecules and so forth in the near future.
pubmed:language
eng
pubmed:journal
pubmed:status
PubMed-not-MEDLINE
pubmed:month
Dec
pubmed:issn
1533-4880
pubmed:author
pubmed:issnType
Print
pubmed:volume
9
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
7407-11
pubmed:year
2009
pubmed:articleTitle
Numerical simulation of a nanoparticle focusing lens in a microfluidic channel by using immersed finite element method.
pubmed:affiliation
SKKU Advanced Institute of Nanotechnology (SAINT), Sungkyunkwan University, 300 Chunchun-dong, Jangan-gu, Suwon Kyonggi-do 440-746, Republic of Korea.
pubmed:publicationType
Journal Article, Research Support, U.S. Gov't, Non-P.H.S., Research Support, Non-U.S. Gov't