Linked Life Data

19908237

Source:http://linkedlifedata.com/resource/pubmed/id/19908237

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
4
pubmed:dateCreated
2010-2-3
pubmed:abstractText
Prostate cancer (PCa) incidence and mortality are disproportionately high among African-American (AA) men. Its detection and perhaps its disparities could be improved through the identification of genetic susceptibility biomarkers within essential biological pathways. Interactions among highly variant genes, central to angiogenesis, may modulate susceptibility for prostate cancer, as previous demonstrated. This study evaluates the interplay among three highly variant genes (i.e., IL-10, TGFbetaR-1, VEGF), their receptors and their influence on PCa within a case-control study consisting of an under-served population.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Mar
pubmed:issn
1097-0045
pubmed:author
pubmed:copyrightInfo
Prostate 70: 341-352, 2010. (c) 2009 Wiley-Liss, Inc.
pubmed:issnType
Electronic
pubmed:day
1
pubmed:volume
70
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
341-52
pubmed:meshHeading
pubmed-meshheading:19908237-Adenocarcinoma, pubmed-meshheading:19908237-Adult, pubmed-meshheading:19908237-African Americans, pubmed-meshheading:19908237-Aged, pubmed-meshheading:19908237-Aged, 80 and over, pubmed-meshheading:19908237-Case-Control Studies, pubmed-meshheading:19908237-Humans, pubmed-meshheading:19908237-Interleukin-10, pubmed-meshheading:19908237-Linkage Disequilibrium, pubmed-meshheading:19908237-Logistic Models, pubmed-meshheading:19908237-Male, pubmed-meshheading:19908237-Middle Aged, pubmed-meshheading:19908237-Polymorphism, Single Nucleotide, pubmed-meshheading:19908237-Prostatic Neoplasms, pubmed-meshheading:19908237-Receptors, Interleukin-10, pubmed-meshheading:19908237-Receptors, Transforming Growth Factor beta, pubmed-meshheading:19908237-Receptors, Vascular Endothelial Growth Factor, pubmed-meshheading:19908237-Risk Factors, pubmed-meshheading:19908237-Transforming Growth Factor beta1, pubmed-meshheading:19908237-Vascular Endothelial Growth Factor A
pubmed:year
2010
pubmed:articleTitle
Interaction among variant vascular endothelial growth factor (VEGF) and its receptor in relation to prostate cancer risk.
pubmed:affiliation
Department of Pharmacology & Toxicology, University of Louisville, Louisville, Kentucky, USA.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't