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| pubmed-article:19906510 | lifeskim:mentions | umls-concept:C0147139 | lld:lifeskim |
| pubmed-article:19906510 | lifeskim:mentions | umls-concept:C0206694 | lld:lifeskim |
| pubmed-article:19906510 | lifeskim:mentions | umls-concept:C0332281 | lld:lifeskim |
| pubmed-article:19906510 | lifeskim:mentions | umls-concept:C0017262 | lld:lifeskim |
| pubmed-article:19906510 | lifeskim:mentions | umls-concept:C0205210 | lld:lifeskim |
| pubmed-article:19906510 | lifeskim:mentions | umls-concept:C2348519 | lld:lifeskim |
| pubmed-article:19906510 | lifeskim:mentions | umls-concept:C1515926 | lld:lifeskim |
| pubmed-article:19906510 | lifeskim:mentions | umls-concept:C2911684 | lld:lifeskim |
| pubmed-article:19906510 | lifeskim:mentions | umls-concept:C0185117 | lld:lifeskim |
| pubmed-article:19906510 | pubmed:issue | 1 | lld:pubmed |
| pubmed-article:19906510 | pubmed:dateCreated | 2010-2-3 | lld:pubmed |
| pubmed-article:19906510 | pubmed:abstractText | Expression of Id-1 (inhibitors of DNA binding/differentiation protein 1) and TSP-1 (thrombospondin-1) in mucoepidermoid carcinoma and their relationship to pathological features and prognosis was studied. Moderately and poorly differentiated groups had significantly higher Id-1 positive expression rate (p<0.05) than well differentiated carcinoma. Stages III-IV showed significant increase of Id-1 positive expression rate (p<0.05) compared with stages I and II. Id-1 positive expression was significantly higher in patients with cervical lymph node metastasis or relapse at 5 years (p<0.05). After that, patients with negative Id-1 expression had significantly higher tumor-free survival than patients with positive expression (p<0.05). Correlation between the expression of Id-1 and TSP-1 in mucoepidermoid carcinoma was negative (p<0.05). Poorly differentiated groups show significantly lower TSP-1 positive expression rate than well differentiated groups (p<0.05). No significant differences of TSP-1 positive expression were detected with clinical stage. TSP-1 positive expression was significantly lower in patients with cervical lymph node metastasis or relapse at 5 years (p<0.05). After 5 years, patients with positive TSP-1 expression had significantly higher tumor-free survival than patients with negative TSP-1. Positive Id-1 expression is associated with high malignancy/poor prognosis; positive TSP-1 expression is associated with low malignancy/good prognosis. Protein expression status may help assess tumor malignancy and patient prognosis. | lld:pubmed |
| pubmed-article:19906510 | pubmed:language | eng | lld:pubmed |
| pubmed-article:19906510 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:19906510 | pubmed:citationSubset | D | lld:pubmed |
| pubmed-article:19906510 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:19906510 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:19906510 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:19906510 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:19906510 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:19906510 | pubmed:month | Jan | lld:pubmed |
| pubmed-article:19906510 | pubmed:issn | 1399-0020 | lld:pubmed |
| pubmed-article:19906510 | pubmed:author | pubmed-author:TatMM | lld:pubmed |
| pubmed-article:19906510 | pubmed:author | pubmed-author:YangSS | lld:pubmed |
| pubmed-article:19906510 | pubmed:author | pubmed-author:WrayH LHL | lld:pubmed |
| pubmed-article:19906510 | pubmed:author | pubmed-author:MAHH | lld:pubmed |
| pubmed-article:19906510 | pubmed:author | pubmed-author:YuTT | lld:pubmed |
| pubmed-article:19906510 | pubmed:author | pubmed-author:BamD SDS | lld:pubmed |
| pubmed-article:19906510 | pubmed:author | pubmed-author:XuanMM | lld:pubmed |
| pubmed-article:19906510 | pubmed:author | pubmed-author:WangC-MCM | lld:pubmed |
| pubmed-article:19906510 | pubmed:author | pubmed-author:HOLTL VLV | lld:pubmed |
| pubmed-article:19906510 | pubmed:author | pubmed-author:TangX-FXF | lld:pubmed |
| pubmed-article:19906510 | pubmed:author | pubmed-author:DunR CRC | lld:pubmed |
| pubmed-article:19906510 | pubmed:author | pubmed-author:GaoQ-HQH | lld:pubmed |
| pubmed-article:19906510 | pubmed:copyrightInfo | Copyright 2009 International Association of Oral and Maxillofacial Surgeons. Published by Elsevier Ltd. All rights reserved. | lld:pubmed |
| pubmed-article:19906510 | pubmed:issnType | Electronic | lld:pubmed |
| pubmed-article:19906510 | pubmed:volume | 39 | lld:pubmed |
| pubmed-article:19906510 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:19906510 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:19906510 | pubmed:pagination | 29-35 | lld:pubmed |
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| pubmed-article:19906510 | pubmed:year | 2010 | lld:pubmed |
| pubmed-article:19906510 | pubmed:articleTitle | The alteration of Id-1 and TSP-1 expression in mucoepidermoid carcinoma associated with its clinical features and prognosis. | lld:pubmed |
| pubmed-article:19906510 | pubmed:affiliation | State Key Laboratory of Oral Diseases, West China College of Stomatology, Sichuan University, Chengdu 610041, Sichuan Province, PR China. | lld:pubmed |
| pubmed-article:19906510 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:19906510 | pubmed:publicationType | Comparative Study | lld:pubmed |
| pubmed-article:19906510 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
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