Linked Life Data

19906130

Source:http://linkedlifedata.com/resource/pubmed/id/19906130

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
5
pubmed:dateCreated
2010-11-19
pubmed:abstractText
Evidence is presented that the buffalo mammary gland contains enzymes that catalyse the synthesis and utilization of glutathione. A significant, inverse correlation (r = 0.79) was detected between colostrum gamma-glutamyltransferase (GGT) and glutathione (GSH), suggesting that the enzyme uses GSH as a substrate for its activity. A similar trend was shown in mammary gland homogenates (r = 0.75). Our results show that GSH is secreted into buffalo colostrum and suggest that the enzyme GGT degrades it. To the authors' knowledge, this is the first demonstration of the involvement of GGT-mediated GSH metabolism in the synthesis of colostrums, which elucidates the role of the enzyme that has always been reported very high in colostrum.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Oct
pubmed:issn
1439-0396
pubmed:author
pubmed:issnType
Electronic
pubmed:volume
94
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
549-51
pubmed:meshHeading
pubmed:year
2010
pubmed:articleTitle
Glutathione concentration and gamma-glutamyltransferase activity in water buffalo colostrum.
pubmed:affiliation
Department of Biological Structures, Functions and Technologies, University of Federico II, Naples, Italy.
pubmed:publicationType
Journal Article