Linked Life Data

19906073

Source:http://linkedlifedata.com/resource/pubmed/id/19906073

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
4
pubmed:dateCreated
2010-5-26
pubmed:abstractText
Vitiligo is a pigmentary skin disorder characterized by a chronic and progressive loss of melanocytes. Although the aetiology of vitiligo is currently unknown, several theories have been proposed to explain the pathogenesis of this disease, including autoimmune, neural, self-destruction, oxidative stress, and genetic theories. Thioredoxin domain containing 5 (TXNDC5) is a newly identified member of the thioredoxin family. TXNDC5 has a protein disulphide isomerase-like domain which plays an important role in protein folding and chaperone activity, against endoplasmic reticulum (ER) stress induced by oxidative stress within the ER.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Apr
pubmed:issn
1365-2133
pubmed:author
pubmed:issnType
Electronic
pubmed:volume
162
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
759-64
pubmed:meshHeading
pubmed:year
2010
pubmed:articleTitle
Association of TXNDC5 gene polymorphisms and susceptibility to nonsegmental vitiligo in the Korean population.
pubmed:affiliation
Department of Dermatology, Kohwang Medical Research Institute, School of Medicine, Kyunghee University, 1 Hoeki-Dong, Dongdaemun-Ku, Seoul 130-702, Korea.
pubmed:publicationType
Journal Article