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rdf:type |
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lifeskim:mentions |
umls-concept:C0004519,
umls-concept:C0009375,
umls-concept:C0012171,
umls-concept:C0018270,
umls-concept:C0026336,
umls-concept:C0034802,
umls-concept:C0035820,
umls-concept:C0079225,
umls-concept:C1367485,
umls-concept:C1510411,
umls-concept:C1514873,
umls-concept:C1519689,
umls-concept:C1546857,
umls-concept:C1556066,
umls-concept:C1619636,
umls-concept:C2003941
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pubmed:issue |
22
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pubmed:dateCreated |
2009-11-13
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pubmed:abstractText |
Colon cancer is a major cause of cancer deaths. Dietary factors contribute substantially to the risk of this malignancy. Western-style diets promote development of azoxymethane-induced colon cancer. Although we showed that epidermal growth factor receptors (EGFR) controlled azoxymethane tumorigenesis in standard fat conditions, the role of EGFR in tumor promotion by high dietary fat has not been examined.
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pubmed:grant |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/Azoxymethane,
http://linkedlifedata.com/resource/pubmed/chemical/Blood Glucose,
http://linkedlifedata.com/resource/pubmed/chemical/Cyclooxygenase 2,
http://linkedlifedata.com/resource/pubmed/chemical/Dextran Sulfate,
http://linkedlifedata.com/resource/pubmed/chemical/Insulin,
http://linkedlifedata.com/resource/pubmed/chemical/Ligands,
http://linkedlifedata.com/resource/pubmed/chemical/Ptgs2 protein, mouse,
http://linkedlifedata.com/resource/pubmed/chemical/Receptor, Epidermal Growth Factor,
http://linkedlifedata.com/resource/pubmed/chemical/Transforming Growth Factor alpha
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pubmed:status |
MEDLINE
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pubmed:month |
Nov
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pubmed:issn |
1078-0432
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pubmed:author |
pubmed-author:AluriLataL,
pubmed-author:BadalShamiramS,
pubmed-author:BissonnetteMarcM,
pubmed-author:CerasiDarioD,
pubmed-author:CerdaSoniaS,
pubmed-author:DelgadoJorgeJ,
pubmed-author:DoughertyUrszulaU,
pubmed-author:FicheraAlessandroA,
pubmed-author:HartJohnJ,
pubmed-author:JosephLorenL,
pubmed-author:KocherginskyMashaM,
pubmed-author:MustafiRebaR,
pubmed-author:SehdevAmikarA,
pubmed-author:TaylorIevaI,
pubmed-author:TekinUmmuhanU,
pubmed-author:ThreadgillDavidD,
pubmed-author:ZhuHongyanH
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pubmed:issnType |
Print
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pubmed:day |
15
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pubmed:volume |
15
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
6780-9
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pubmed:dateRevised |
2011-11-17
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pubmed:meshHeading |
pubmed-meshheading:19903783-Animals,
pubmed-meshheading:19903783-Azoxymethane,
pubmed-meshheading:19903783-Blood Glucose,
pubmed-meshheading:19903783-Colonic Neoplasms,
pubmed-meshheading:19903783-Cyclooxygenase 2,
pubmed-meshheading:19903783-Dextran Sulfate,
pubmed-meshheading:19903783-Gene Expression Regulation, Neoplastic,
pubmed-meshheading:19903783-Insulin,
pubmed-meshheading:19903783-Insulin Resistance,
pubmed-meshheading:19903783-Ligands,
pubmed-meshheading:19903783-Mice,
pubmed-meshheading:19903783-Mice, Inbred C57BL,
pubmed-meshheading:19903783-Point Mutation,
pubmed-meshheading:19903783-Receptor, Epidermal Growth Factor,
pubmed-meshheading:19903783-Transforming Growth Factor alpha
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pubmed:year |
2009
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pubmed:articleTitle |
Epidermal growth factor receptor is required for colonic tumor promotion by dietary fat in the azoxymethane/dextran sulfate sodium model: roles of transforming growth factor-{alpha} and PTGS2.
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pubmed:affiliation |
Departments of Medicine, Health Studies, Surgery, and Pathology, University of Chicago, Chicago, Illinois , USA.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't,
Research Support, N.I.H., Extramural
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