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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
3
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pubmed:dateCreated |
2010-4-8
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pubmed:abstractText |
Hailey-Hailey disease (HHD) is an autosomal dominant disorder characterized by suprabasal cutaneous cell separation (acantholysis) leading to the development of erosive and oozing skin lesions. While a strong relationship exists between mutations in the gene that encodes the Ca(2+)/Mn(2+)-adenosine triphosphatase ATP2C1 and HHD, we still have little understanding of how these mutations affect manifestations of the disease.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Mar
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pubmed:issn |
1365-2133
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pubmed:author |
pubmed-author:BarbieriLL,
pubmed-author:BarboniLL,
pubmed-author:BiolcatiGG,
pubmed-author:CeccarelliSS,
pubmed-author:CialfiSS,
pubmed-author:De BernardiMM,
pubmed-author:FratiLL,
pubmed-author:GrammaticoPP,
pubmed-author:GulinoAA,
pubmed-author:MagrelliAA,
pubmed-author:MarcheseCC,
pubmed-author:OlivieroCC,
pubmed-author:PalleschiCC,
pubmed-author:SalvatoreMM,
pubmed-author:ScrepantiII,
pubmed-author:TaloraCC,
pubmed-author:TaruscioDD,
pubmed-author:UccellettiDD
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pubmed:issnType |
Electronic
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pubmed:volume |
162
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
518-26
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pubmed:dateRevised |
2010-11-18
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pubmed:meshHeading |
pubmed-meshheading:19903178-Calcium,
pubmed-meshheading:19903178-Calcium-Transporting ATPases,
pubmed-meshheading:19903178-DNA Mutational Analysis,
pubmed-meshheading:19903178-Homeostasis,
pubmed-meshheading:19903178-Humans,
pubmed-meshheading:19903178-Oxidative Stress,
pubmed-meshheading:19903178-Pedigree,
pubmed-meshheading:19903178-Pemphigus, Benign Familial,
pubmed-meshheading:19903178-Phenotype,
pubmed-meshheading:19903178-Receptors, Notch,
pubmed-meshheading:19903178-Reverse Transcriptase Polymerase Chain Reaction
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pubmed:year |
2010
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pubmed:articleTitle |
Complex multipathways alterations and oxidative stress are associated with Hailey-Hailey disease.
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pubmed:affiliation |
Department of Experimental Medicine, University La Sapienza, 00161, Rome, Italy.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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