rdf:type |
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lifeskim:mentions |
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pubmed:issue |
21
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pubmed:dateCreated |
2009-11-25
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pubmed:databankReference |
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pubmed:abstractText |
Individuals with diabetes mellitus have an increased risk of cardiovascular disease and exhibit platelet hyperreactivity, increasing their resistance to antithrombotic therapies such as aspirin and clopidogrel. Reconstituted high-density lipoprotein (rHDL) has short-term beneficial effects on atherosclerotic plaques, but whether it can effectively reduce the reactivity of diabetic platelets is not known.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
AIM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/ATP binding cassette transporter 1,
http://linkedlifedata.com/resource/pubmed/chemical/ATP-Binding Cassette Transporters,
http://linkedlifedata.com/resource/pubmed/chemical/Cholera Toxin,
http://linkedlifedata.com/resource/pubmed/chemical/Cholesterol,
http://linkedlifedata.com/resource/pubmed/chemical/Lipoproteins, HDL,
http://linkedlifedata.com/resource/pubmed/chemical/Recombinant Proteins,
http://linkedlifedata.com/resource/pubmed/chemical/SCARB1 protein, human,
http://linkedlifedata.com/resource/pubmed/chemical/Scavenger Receptors, Class B
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pubmed:status |
MEDLINE
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pubmed:month |
Nov
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pubmed:issn |
1524-4539
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pubmed:author |
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pubmed:issnType |
Electronic
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pubmed:day |
24
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pubmed:volume |
120
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
2095-104
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pubmed:meshHeading |
pubmed-meshheading:19901191-ATP-Binding Cassette Transporters,
pubmed-meshheading:19901191-Blood Platelets,
pubmed-meshheading:19901191-Cholera Toxin,
pubmed-meshheading:19901191-Cholesterol,
pubmed-meshheading:19901191-Diabetes Mellitus, Type 2,
pubmed-meshheading:19901191-Dose-Response Relationship, Drug,
pubmed-meshheading:19901191-Humans,
pubmed-meshheading:19901191-Lipoproteins, HDL,
pubmed-meshheading:19901191-Membrane Microdomains,
pubmed-meshheading:19901191-Middle Aged,
pubmed-meshheading:19901191-Platelet Aggregation,
pubmed-meshheading:19901191-Recombinant Proteins,
pubmed-meshheading:19901191-Scavenger Receptors, Class B,
pubmed-meshheading:19901191-Thrombosis
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pubmed:year |
2009
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pubmed:articleTitle |
Reconstituted high-density lipoprotein attenuates platelet function in individuals with type 2 diabetes mellitus by promoting cholesterol efflux.
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pubmed:affiliation |
Diabetes Complications Laboratory, Baker IDI Heart and Diabetes Institute, PO Box 6492, St Kilda Rd Central, Melbourne, Australia 8008. anna.calkin@bakeridi.edu.au
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pubmed:publicationType |
Journal Article,
Clinical Trial,
Research Support, Non-U.S. Gov't
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