Linked Life Data

19900897

Source:http://linkedlifedata.com/resource/pubmed/id/19900897

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
5952
pubmed:dateCreated
2009-11-10
pubmed:abstractText
The pathogen Batrachochytrium dendrobatidis (Bd), which causes the skin disease chytridiomycosis, is one of the few highly virulent fungi in vertebrates and has been implicated in worldwide amphibian declines. However, the mechanism by which Bd causes death has not been determined. We show that Bd infection is associated with pathophysiological changes that lead to mortality in green tree frogs (Litoria caerulea). In diseased individuals, electrolyte transport across the epidermis was inhibited by >50%, plasma sodium and potassium concentrations were respectively reduced by approximately 20% and approximately 50%, and asystolic cardiac arrest resulted in death. Because the skin is critical in maintaining amphibian homeostasis, disruption to cutaneous function may be the mechanism by which Bd produces morbidity and mortality across a wide range of phylogenetically distant amphibian taxa.
pubmed:commentsCorrections
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Oct
pubmed:issn
1095-9203
pubmed:author
pubmed:issnType
Electronic
pubmed:day
23
pubmed:volume
326
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
582-5
pubmed:meshHeading
pubmed:year
2009
pubmed:articleTitle
Pathogenesis of chytridiomycosis, a cause of catastrophic amphibian declines.
pubmed:affiliation
School of Public Health, Tropical Medicine and Rehabilitation Sciences, Amphibian Disease Ecology Group, James Cook University, Townsville, QLD 4811, Australia. jamie.voyles@gmail.com
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't