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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
5
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pubmed:dateCreated |
2009-11-10
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pubmed:abstractText |
Deregulation of apoptosis is one of the hallmarks of cancers. Inactivation of cancer cell apoptosis by somatic mutations has been reported in several cancers. Caspase-10 activation is important in the initiation phase of apoptosis. The aim of this study was to explore whether CASP10 gene that encodes caspase-10 is somatically mutated in acute adulthood leukaemias and multiple myelomas (MMs).
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pubmed:language |
eng
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pubmed:journal |
|
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pubmed:citationSubset |
IM
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pubmed:chemical |
|
|
pubmed:status |
MEDLINE
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pubmed:issn |
1465-3931
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pubmed:author |
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pubmed:issnType |
Electronic
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pubmed:volume |
41
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
484-7
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pubmed:meshHeading |
pubmed-meshheading:19900088-Adult,
pubmed-meshheading:19900088-Aged,
pubmed-meshheading:19900088-Aged, 80 and over,
pubmed-meshheading:19900088-Apoptosis,
pubmed-meshheading:19900088-Caspase 10,
pubmed-meshheading:19900088-DNA Mutational Analysis,
pubmed-meshheading:19900088-Humans,
pubmed-meshheading:19900088-Leukemia,
pubmed-meshheading:19900088-Middle Aged,
pubmed-meshheading:19900088-Multiple Myeloma,
pubmed-meshheading:19900088-Mutation,
pubmed-meshheading:19900088-Polymorphism, Single-Stranded Conformational,
pubmed-meshheading:19900088-Reverse Transcriptase Polymerase Chain Reaction,
pubmed-meshheading:19900088-Young Adult
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pubmed:year |
2009
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pubmed:articleTitle |
Mutational analysis of CASP10 gene in acute leukaemias and multiple myelomas.
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pubmed:affiliation |
Department of Pathology, College of Medicine, The Catholic University of Korea, Seoul, Korea.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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