|
rdf:type |
|
|
lifeskim:mentions |
|
|
pubmed:issue |
1-2
|
|
pubmed:dateCreated |
2010-2-1
|
|
pubmed:abstractText |
In patients from two clinical trials, we investigated the associations of single nucleotide polymorphisms (SNPs) in candidate genes with prolactin level changes during treatment with olanzapine/fluoxetine combination. In both cohorts, three dopamine receptor D2 (DRD2) SNPs were associated with prolactin changes. DRD2 may influence susceptibility to hyperprolactinemia associated with antipsychotic treatment.
|
|
pubmed:language |
eng
|
|
pubmed:journal |
|
|
pubmed:citationSubset |
IM
|
|
pubmed:chemical |
|
|
pubmed:status |
MEDLINE
|
|
pubmed:month |
Jan
|
|
pubmed:issn |
0165-1781
|
|
pubmed:author |
|
|
pubmed:issnType |
Print
|
|
pubmed:day |
30
|
|
pubmed:volume |
175
|
|
pubmed:owner |
NLM
|
|
pubmed:authorsComplete |
Y
|
|
pubmed:pagination |
171-2
|
|
pubmed:meshHeading |
pubmed-meshheading:19896213-Adult,
pubmed-meshheading:19896213-Aged,
pubmed-meshheading:19896213-Analysis of Variance,
pubmed-meshheading:19896213-Antipsychotic Agents,
pubmed-meshheading:19896213-Benzodiazepines,
pubmed-meshheading:19896213-Depression,
pubmed-meshheading:19896213-Dose-Response Relationship, Drug,
pubmed-meshheading:19896213-Double-Blind Method,
pubmed-meshheading:19896213-Drug Combinations,
pubmed-meshheading:19896213-European Continental Ancestry Group,
pubmed-meshheading:19896213-Female,
pubmed-meshheading:19896213-Fluoxetine,
pubmed-meshheading:19896213-Genome-Wide Association Study,
pubmed-meshheading:19896213-Humans,
pubmed-meshheading:19896213-Hyperprolactinemia,
pubmed-meshheading:19896213-Male,
pubmed-meshheading:19896213-Middle Aged,
pubmed-meshheading:19896213-Polymorphism, Single Nucleotide,
pubmed-meshheading:19896213-Prolactin,
pubmed-meshheading:19896213-Receptors, Dopamine D2,
pubmed-meshheading:19896213-Young Adult
|
|
pubmed:year |
2010
|
|
pubmed:articleTitle |
Genetic associations of prolactin increase in olanzapine/fluoxetine combination-treated patients.
|
|
pubmed:affiliation |
Lilly USA, LLC, Indianapolis, IN 46285, USA. houston_john_p@lilly.com
|
|
pubmed:publicationType |
Journal Article,
Clinical Trial,
Randomized Controlled Trial,
Multicenter Study
|
