Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
4
pubmed:dateCreated
2010-2-22
pubmed:abstractText
CD9 has been shown to be differentially expressed in childhood TEL/AML1-positive acute lymphoblastic leukemia (ALL). We confirmed this finding in large Affymetrix data sets and in 80 new cases at both RNA and protein levels. Moreover, we showed that mean fluorescence intensity of CD9 by flow cytometry can distinguish TEL/AML1-positive ALL from other BCP-ALL. Using ROC analysis, the most efficient model for predicting TEL/AML1-positive ALL combined CD9 (mean fluorescence intensity <or=20) and CD10 values (positive cells >40%). Finally, we propose a faster procedure for optimizing the diagnosis of childhood BCP-ALL subgroups.
pubmed:commentsCorrections
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Apr
pubmed:issn
1873-5835
pubmed:author
pubmed:copyrightInfo
Copyright (c) 2009 Elsevier Ltd. All rights reserved.
pubmed:issnType
Electronic
pubmed:volume
34
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
430-7
pubmed:dateRevised
2011-11-17
pubmed:meshHeading
pubmed-meshheading:19896186-Algorithms, pubmed-meshheading:19896186-Antigens, CD, pubmed-meshheading:19896186-Antigens, CD9, pubmed-meshheading:19896186-Child, pubmed-meshheading:19896186-Core Binding Factor Alpha 2 Subunit, pubmed-meshheading:19896186-Decision Support Techniques, pubmed-meshheading:19896186-False Positive Reactions, pubmed-meshheading:19896186-Gene Expression Profiling, pubmed-meshheading:19896186-Gene Expression Regulation, Leukemic, pubmed-meshheading:19896186-Humans, pubmed-meshheading:19896186-Membrane Glycoproteins, pubmed-meshheading:19896186-Oligonucleotide Array Sequence Analysis, pubmed-meshheading:19896186-Oncogene Proteins, Fusion, pubmed-meshheading:19896186-Precursor Cell Lymphoblastic Leukemia-Lymphoma, pubmed-meshheading:19896186-Prognosis, pubmed-meshheading:19896186-Time Factors, pubmed-meshheading:19896186-Tumor Cells, Cultured, pubmed-meshheading:19896186-Tumor Markers, Biological
pubmed:year
2010
pubmed:articleTitle
CD9 expression can be used to predict childhood TEL/AML1-positive acute lymphoblastic leukemia: proposal for an accelerated diagnostic flowchart.
pubmed:affiliation
Centre National de Recherche Scientifique, Unité Mixte de Recherche 6061 Laboratoire de Génétique et Développement, Equipe Régulation Transcriptionnelle et Oncogenèse, Université de Rennes-1, Rennes Cedex, France.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't, Validation Studies