rdf:type |
|
lifeskim:mentions |
|
pubmed:issue |
3-4
|
pubmed:dateCreated |
2010-1-27
|
pubmed:abstractText |
FAS-670 A/G single nucleotide polymorphism has been demonstrated to affect the expression of FAS gene by altering the transcriptional activity of FAS gene promoter. Downregulation of FAS with resultant resistance to death signals has been found in many cancers. We carried out a case-control study to investigate the biological significance of this polymorphism in nasopharyngeal carcinoma (NPC).
|
pubmed:language |
eng
|
pubmed:journal |
|
pubmed:citationSubset |
IM
|
pubmed:chemical |
|
pubmed:status |
MEDLINE
|
pubmed:month |
Feb
|
pubmed:issn |
1873-3492
|
pubmed:author |
|
pubmed:copyrightInfo |
Copyright 2009 Elsevier B.V. All rights reserved.
|
pubmed:issnType |
Electronic
|
pubmed:volume |
411
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
179-83
|
pubmed:meshHeading |
pubmed-meshheading:19895798-Antigens, CD95,
pubmed-meshheading:19895798-Asian Continental Ancestry Group,
pubmed-meshheading:19895798-Case-Control Studies,
pubmed-meshheading:19895798-China,
pubmed-meshheading:19895798-Female,
pubmed-meshheading:19895798-Gene Frequency,
pubmed-meshheading:19895798-Genetic Predisposition to Disease,
pubmed-meshheading:19895798-Genotype,
pubmed-meshheading:19895798-Humans,
pubmed-meshheading:19895798-Male,
pubmed-meshheading:19895798-Middle Aged,
pubmed-meshheading:19895798-Nasopharyngeal Neoplasms,
pubmed-meshheading:19895798-Neoplasm Metastasis,
pubmed-meshheading:19895798-Polymorphism, Single Nucleotide,
pubmed-meshheading:19895798-Tumor Markers, Biological
|
pubmed:year |
2010
|
pubmed:articleTitle |
FAS-670A/G polymorphism: A biomarker for the metastasis of nasopharyngeal carcinoma in a Chinese population.
|
pubmed:affiliation |
Cancer Center, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430022, Hubei Province, China.
|
pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
|