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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
3
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pubmed:dateCreated |
2010-4-16
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pubmed:abstractText |
Transglutaminase 2 (TG2) is important for the deposition and stability of the extracellular matrix via effects on cross-linking of matrix proteins and transforming growth factor beta (TGFbeta) activity. The purpose of this study was to investigate the effect of TG2 deficiency on the composi- tion of atherosclerotic plaques.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:issn |
1423-0135
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pubmed:author |
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pubmed:copyrightInfo |
Copyright 2009 S. Karger AG, Basel.
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pubmed:issnType |
Electronic
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pubmed:volume |
47
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
231-40
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pubmed:meshHeading |
pubmed-meshheading:19893320-Animals,
pubmed-meshheading:19893320-Apolipoproteins E,
pubmed-meshheading:19893320-Atherosclerosis,
pubmed-meshheading:19893320-Collagen,
pubmed-meshheading:19893320-Disease Models, Animal,
pubmed-meshheading:19893320-Disease Progression,
pubmed-meshheading:19893320-Extracellular Matrix Proteins,
pubmed-meshheading:19893320-Female,
pubmed-meshheading:19893320-Fibrosis,
pubmed-meshheading:19893320-GTP-Binding Proteins,
pubmed-meshheading:19893320-Inflammation,
pubmed-meshheading:19893320-Macrophages,
pubmed-meshheading:19893320-Mice,
pubmed-meshheading:19893320-Mice, Inbred C57BL,
pubmed-meshheading:19893320-Mice, Knockout,
pubmed-meshheading:19893320-Rupture,
pubmed-meshheading:19893320-Time Factors,
pubmed-meshheading:19893320-Transforming Growth Factor beta,
pubmed-meshheading:19893320-Transglutaminases
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pubmed:year |
2010
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pubmed:articleTitle |
Transglutaminase 2 deficiency decreases plaque fibrosis and increases plaque inflammation in apolipoprotein-E-deficient mice.
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pubmed:affiliation |
Division of Cardiology, Antwerp University Hospital, Edegem, Belgium. jozef.vanherck@ua.ac.be
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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