|
rdf:type |
|
|
lifeskim:mentions |
|
|
pubmed:issue |
5954
|
|
pubmed:dateCreated |
2009-11-6
|
|
pubmed:abstractText |
We report a high-quality draft sequence of the genome of the horse (Equus caballus). The genome is relatively repetitive but has little segmental duplication. Chromosomes appear to have undergone few historical rearrangements: 53% of equine chromosomes show conserved synteny to a single human chromosome. Equine chromosome 11 is shown to have an evolutionary new centromere devoid of centromeric satellite DNA, suggesting that centromeric function may arise before satellite repeat accumulation. Linkage disequilibrium, showing the influences of early domestication of large herds of female horses, is intermediate in length between dog and human, and there is long-range haplotype sharing among breeds.
|
|
pubmed:language |
eng
|
|
pubmed:journal |
|
|
pubmed:citationSubset |
IM
|
|
pubmed:status |
MEDLINE
|
|
pubmed:month |
Nov
|
|
pubmed:issn |
1095-9203
|
|
pubmed:author |
pubmed-author:AdelsonD LDL,
pubmed-author:AnderssonLL,
pubmed-author:AntczakD FDF,
pubmed-author:BaileyEE,
pubmed-author:BelloneR RRR,
pubmed-author:BiagiTT,
pubmed-author:BinnsM MMM,
pubmed-author:BlöckerHH,
pubmed-author:Broad Institute Genome Sequencing Platform,
pubmed-author:Broad Institute Whole Genome Assembly Team,
pubmed-author:ChowdharyB PBP,
pubmed-author:ColemanS JSJ,
pubmed-author:Della ValleGG,
pubmed-author:DistlOO,
pubmed-author:EdgarR CRC,
pubmed-author:FrycSS,
pubmed-author:GarberMM,
pubmed-author:GiulottoEE,
pubmed-author:GnerreSS,
pubmed-author:GuérinGG,
pubmed-author:HasegawaTT,
pubmed-author:HillE WEW,
pubmed-author:ImslandFF,
pubmed-author:JurkaJJ,
pubmed-author:KiialainenAA,
pubmed-author:LanderE SES,
pubmed-author:LearT LTL,
pubmed-author:LeebTT,
pubmed-author:Lindblad-TohKK,
pubmed-author:LindgrenGG,
pubmed-author:LiuJJ,
pubmed-author:MacLeodJ NJN,
pubmed-author:MagnaniEE,
pubmed-author:MauceliEE,
pubmed-author:MickelsonJ RJR,
pubmed-author:MurrayJJ,
pubmed-author:NergadzeS GSG,
pubmed-author:OnofrioRR,
pubmed-author:PedroniSS,
pubmed-author:PenedoM C TMC,
pubmed-author:PirasM FMF,
pubmed-author:RøedK HKH,
pubmed-author:RaisonJ MJM,
pubmed-author:RaudseppTT,
pubmed-author:RocchiMM,
pubmed-author:RyderO AOA,
pubmed-author:SearleSS,
pubmed-author:SharpeTT,
pubmed-author:SigurdssonSS,
pubmed-author:SkowLL,
pubmed-author:SwinburneJ EJE,
pubmed-author:SyvänenA CAC,
pubmed-author:TozakiTT,
pubmed-author:ValbergS JSJ,
pubmed-author:VaudinMM,
pubmed-author:VogelJJ,
pubmed-author:WadeC MCM,
pubmed-author:WhiteJ RJR,
pubmed-author:ZodyM CMC,
pubmed-author:ZoliMM
|
|
pubmed:issnType |
Electronic
|
|
pubmed:day |
6
|
|
pubmed:volume |
326
|
|
pubmed:owner |
NLM
|
|
pubmed:authorsComplete |
Y
|
|
pubmed:pagination |
865-7
|
|
pubmed:meshHeading |
pubmed-meshheading:19892987-Humans,
pubmed-meshheading:19892987-Animals,
pubmed-meshheading:19892987-Dogs,
pubmed-meshheading:19892987-Horses,
pubmed-meshheading:19892987-Female,
pubmed-meshheading:19892987-Animals, Domestic,
pubmed-meshheading:19892987-Genes,
pubmed-meshheading:19892987-Chromosome Mapping,
pubmed-meshheading:19892987-Chromosomes, Mammalian,
pubmed-meshheading:19892987-Evolution, Molecular,
pubmed-meshheading:19892987-Molecular Sequence Data,
pubmed-meshheading:19892987-Phylogeny,
pubmed-meshheading:19892987-Sequence Analysis, DNA,
pubmed-meshheading:19892987-Haplotypes,
pubmed-meshheading:19892987-Repetitive Sequences, Nucleic Acid,
pubmed-meshheading:19892987-Centromere,
pubmed-meshheading:19892987-Genome,
pubmed-meshheading:19892987-Computational Biology,
pubmed-meshheading:19892987-Synteny
|
