Linked Life Data

19890334

Source:http://linkedlifedata.com/resource/pubmed/id/19890334

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
12
pubmed:dateCreated
2009-11-25
pubmed:abstractText
Aberrations in proteins that control apoptosis and cell survival are common in cancer. These aberrations often reside in signalling proteins that control the activation of the apoptotic machinery or in the Bcl-2 family of proteins that control caspase activation. Recent evidence suggests that caspase 2, one of the most evolutionarily conserved caspases, may have multiple roles in the DNA damage response, cell cycle regulation and tumour suppression. These findings are unexpected and have important implications for our understanding of tumorigenesis and the treatment of cancer.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Dec
pubmed:issn
1474-1768
pubmed:author
pubmed:issnType
Electronic
pubmed:volume
9
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
897-903
pubmed:meshHeading
pubmed:year
2009
pubmed:articleTitle
Caspase 2 in apoptosis, the DNA damage response and tumour suppression: enigma no more?
pubmed:affiliation
Centre for Cancer Biology, Department of Haematology, SA Pathology, Frome Road, Adelaide, SA5000, Australia. sharad.kumar@health.sa.gov.au
pubmed:publicationType
Journal Article, Review, Research Support, Non-U.S. Gov't