Linked Life Data

19886810

Source:http://linkedlifedata.com/resource/pubmed/id/19886810

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:dateCreated
2009-11-20
pubmed:abstractText
The cohesin complex is a major constituent of interphase and mitotic chromosomes. Apart from its role in mediating sister chromatid cohesion, it is also important for DNA double-strand-break repair and transcriptional control. The functions of cohesin are regulated by phosphorylation, acetylation, ATP hydrolysis, and site-specific proteolysis. Recent evidence suggests that cohesin acts as a novel topological device that traps chromosomal DNA within a large tripartite ring formed by its core subunits.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
1545-2948
pubmed:author
pubmed:issnType
Electronic
pubmed:volume
43
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
525-58
pubmed:meshHeading
pubmed:year
2009
pubmed:articleTitle
Cohesin: its roles and mechanisms.
pubmed:affiliation
Department of Biochemistry, University of Oxford, Oxford OX1 3QU, United Kingdom. kim.nasmyth@bioch.ox.ac.uk
pubmed:publicationType
Journal Article, Review