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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
4
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pubmed:dateCreated |
2010-8-6
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pubmed:abstractText |
Carcinogenesis is a multistep process involving the accumulation of genetic and molecular abnormalities. It has been suggested that there is a relationship between telomere attrition in the early stages of carcinogenesis and activation of the DNA damage response machinery. We explored telomere length modification and damage response pathway activation at 3 steps of breast carcinogenesis.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Aug
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pubmed:issn |
1537-453X
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pubmed:author |
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pubmed:issnType |
Electronic
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pubmed:volume |
33
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
341-5
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pubmed:meshHeading |
pubmed-meshheading:19884805-Adult,
pubmed-meshheading:19884805-Aged,
pubmed-meshheading:19884805-Breast,
pubmed-meshheading:19884805-Breast Neoplasms,
pubmed-meshheading:19884805-DNA Damage,
pubmed-meshheading:19884805-DNA Repair,
pubmed-meshheading:19884805-Female,
pubmed-meshheading:19884805-Histones,
pubmed-meshheading:19884805-Humans,
pubmed-meshheading:19884805-Middle Aged,
pubmed-meshheading:19884805-Neoplasm Invasiveness,
pubmed-meshheading:19884805-Precancerous Conditions,
pubmed-meshheading:19884805-Telomere
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pubmed:year |
2010
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pubmed:articleTitle |
DNA damage repair and telomere length in normal breast, preneoplastic lesions, and invasive cancer.
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pubmed:affiliation |
Département des Science du Vinvant-Laboratoire de radiobiologie et oncologie, CEA, Fontenay-aux-Roses, France.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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