Source:http://linkedlifedata.com/resource/pubmed/id/19883099
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
23
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pubmed:dateCreated |
2009-11-30
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pubmed:abstractText |
All four diastereomers of the trisubstituted piperidine-alkaloids of the veratramine and jervine type were synthesized with complete stereocontrol starting from enantiopure citronellic acids. The flexible, high-yielding, and scalable route described here will facilitate convergent syntheses and give access to analogues of cyclopamine and other biologically active and diverse steroid alkaloids.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/Biological Agents,
http://linkedlifedata.com/resource/pubmed/chemical/Piperidines,
http://linkedlifedata.com/resource/pubmed/chemical/Veratrum Alkaloids,
http://linkedlifedata.com/resource/pubmed/chemical/cyclopamine,
http://linkedlifedata.com/resource/pubmed/chemical/jervine,
http://linkedlifedata.com/resource/pubmed/chemical/veratramine
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pubmed:status |
MEDLINE
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pubmed:month |
Dec
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pubmed:issn |
1523-7052
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pubmed:author | |
pubmed:issnType |
Electronic
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pubmed:day |
3
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pubmed:volume |
11
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
5410-2
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pubmed:dateRevised |
2011-11-17
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pubmed:meshHeading | |
pubmed:year |
2009
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pubmed:articleTitle |
Synthesis of all diastereomers of the piperidine--alkaloid substructure of cyclopamine.
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pubmed:affiliation |
Institut für Organische Chemie, Universität Leipzig, 04103 Leipzig, Germany.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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