| pubmed-article:19880783 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:19880783 | lifeskim:mentions | umls-concept:C0013018 | lld:lifeskim |
| pubmed-article:19880783 | lifeskim:mentions | umls-concept:C0150369 | lld:lifeskim |
| pubmed-article:19880783 | lifeskim:mentions | umls-concept:C0333678 | lld:lifeskim |
| pubmed-article:19880783 | lifeskim:mentions | umls-concept:C0005773 | lld:lifeskim |
| pubmed-article:19880783 | lifeskim:mentions | umls-concept:C1504389 | lld:lifeskim |
| pubmed-article:19880783 | lifeskim:mentions | umls-concept:C0035020 | lld:lifeskim |
| pubmed-article:19880783 | lifeskim:mentions | umls-concept:C1511790 | lld:lifeskim |
| pubmed-article:19880783 | lifeskim:mentions | umls-concept:C1332710 | lld:lifeskim |
| pubmed-article:19880783 | lifeskim:mentions | umls-concept:C1947906 | lld:lifeskim |
| pubmed-article:19880783 | lifeskim:mentions | umls-concept:C1515895 | lld:lifeskim |
| pubmed-article:19880783 | lifeskim:mentions | umls-concept:C0332324 | lld:lifeskim |
| pubmed-article:19880783 | pubmed:issue | 11 | lld:pubmed |
| pubmed-article:19880783 | pubmed:dateCreated | 2009-11-2 | lld:pubmed |
| pubmed-article:19880783 | pubmed:abstractText | Analysis of donor chimerism is an important diagnostic tool to assess the risk of relapse after allogeneic stem cell transplantation, especially in patients lacking a specific marker suitable for monitoring of minimal residual disease. We prospectively investigated the predictive value of donor chimerism analyses in sorted CD34(+) peripheral blood cells in 90 patients with acute leukemia and myelodysplastic syndrome. The cumulative incidence of relapse after four years was significantly increased in cases with decreasing or incomplete CD34(+) donor chimerism (57% vs. 18%, p=0.0001). Multivariate analysis confirmed decreasing CD34(+) donor chimerism as an independent predictor of relapse and inferior survival. The interval between a decrease of CD34(+) chimerism of less than 80% and hematologic relapse was 61 days (range 0-567). Monitoring of CD34(+) donor chimerism in the peripheral blood allows prediction of imminent relapse after allogeneic stem cell transplantation even when a disease-specific marker is lacking. | lld:pubmed |
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| pubmed-article:19880783 | pubmed:language | eng | lld:pubmed |
| pubmed-article:19880783 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:19880783 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:19880783 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:19880783 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:19880783 | pubmed:month | Nov | lld:pubmed |
| pubmed-article:19880783 | pubmed:issn | 1592-8721 | lld:pubmed |
| pubmed-article:19880783 | pubmed:author | pubmed-author:FauserAxel... | lld:pubmed |
| pubmed-article:19880783 | pubmed:author | pubmed-author:KleinStefanS | lld:pubmed |
| pubmed-article:19880783 | pubmed:author | pubmed-author:ScheteligJoha... | lld:pubmed |
| pubmed-article:19880783 | pubmed:author | pubmed-author:ThiedeChristi... | lld:pubmed |
| pubmed-article:19880783 | pubmed:author | pubmed-author:BornhäuserMar... | lld:pubmed |
| pubmed-article:19880783 | pubmed:author | pubmed-author:EhningerGerha... | lld:pubmed |
| pubmed-article:19880783 | pubmed:author | pubmed-author:MartinHansH | lld:pubmed |
| pubmed-article:19880783 | pubmed:author | pubmed-author:MohrBrigitteB | lld:pubmed |
| pubmed-article:19880783 | pubmed:author | pubmed-author:BrendelCornel... | lld:pubmed |
| pubmed-article:19880783 | pubmed:author | pubmed-author:PlatzbeckerUw... | lld:pubmed |
| pubmed-article:19880783 | pubmed:author | pubmed-author:SchaichMarkus... | lld:pubmed |
| pubmed-article:19880783 | pubmed:author | pubmed-author:IllmerThomasT | lld:pubmed |
| pubmed-article:19880783 | pubmed:author | pubmed-author:TheuserCatrin... | lld:pubmed |
| pubmed-article:19880783 | pubmed:author | pubmed-author:KiehlMichael... | lld:pubmed |
| pubmed-article:19880783 | pubmed:author | pubmed-author:KianiAlexande... | lld:pubmed |
| pubmed-article:19880783 | pubmed:author | pubmed-author:BugGesineG | lld:pubmed |
| pubmed-article:19880783 | pubmed:author | pubmed-author:OelschlaegelU... | lld:pubmed |
| pubmed-article:19880783 | pubmed:author | pubmed-author:LutterbeckKar... | lld:pubmed |
| pubmed-article:19880783 | pubmed:issnType | Electronic | lld:pubmed |
| pubmed-article:19880783 | pubmed:volume | 94 | lld:pubmed |
| pubmed-article:19880783 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:19880783 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:19880783 | pubmed:pagination | 1613-7 | lld:pubmed |
| pubmed-article:19880783 | pubmed:dateRevised | 2010-9-28 | lld:pubmed |
| pubmed-article:19880783 | pubmed:meshHeading | pubmed-meshheading:19880783... | lld:pubmed |
| pubmed-article:19880783 | pubmed:meshHeading | pubmed-meshheading:19880783... | lld:pubmed |
| pubmed-article:19880783 | pubmed:meshHeading | pubmed-meshheading:19880783... | lld:pubmed |
| pubmed-article:19880783 | pubmed:meshHeading | pubmed-meshheading:19880783... | lld:pubmed |
| pubmed-article:19880783 | pubmed:meshHeading | pubmed-meshheading:19880783... | lld:pubmed |
| pubmed-article:19880783 | pubmed:meshHeading | pubmed-meshheading:19880783... | lld:pubmed |
| pubmed-article:19880783 | pubmed:meshHeading | pubmed-meshheading:19880783... | lld:pubmed |
| pubmed-article:19880783 | pubmed:meshHeading | pubmed-meshheading:19880783... | lld:pubmed |
| pubmed-article:19880783 | pubmed:meshHeading | pubmed-meshheading:19880783... | lld:pubmed |
| pubmed-article:19880783 | pubmed:meshHeading | pubmed-meshheading:19880783... | lld:pubmed |
| pubmed-article:19880783 | pubmed:meshHeading | pubmed-meshheading:19880783... | lld:pubmed |
| pubmed-article:19880783 | pubmed:year | 2009 | lld:pubmed |
| pubmed-article:19880783 | pubmed:articleTitle | Monitoring of donor chimerism in sorted CD34+ peripheral blood cells allows the sensitive detection of imminent relapse after allogeneic stem cell transplantation. | lld:pubmed |
| pubmed-article:19880783 | pubmed:affiliation | Medizinische Klinik und Poliklinik I, University Hospital, Dresden, Germany. martin.bornhaeuser@uniklinikum-dresden.de | lld:pubmed |
| pubmed-article:19880783 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:19880783 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:19880783 | lld:pubmed |
