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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
1
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pubmed:dateCreated |
1991-2-20
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pubmed:abstractText |
Serum deoxythymidine kinase activities (s-TK) of the patients with adult T-cell leukemia (ATL), carriers and healthy persons were measured, using a recently developed TK assay with 125I-iodo-deoxyuridine as a substrate. The mean s-TK values were 3.3 +/- 2.7 U/l (n = 21) in normal subjects (HTLV-1(-)), 4.7 +/- 5.0 U/l (n = 35) in carriers, 9.8 U/l (n = 3) in smoldering ATL and 26.7 U/l (n = 6) in chronic ATL. In the patients with acute ATL, the mean s-TK values before and after chemotherapy were 80.9 U/l (n = 2) and 11.6 U/l (n = 4), respectively. In the follow-up studies of the patients with acute ATL, the changes of s-TK levels revealed earlier than those of serum LDH levels. It is suggested that s-TK activity is more useful than LDH as a parameter of monitoring treatment in ATL.
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pubmed:language |
jpn
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Jan
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pubmed:issn |
0385-0684
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
18
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
63-7
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pubmed:dateRevised |
2007-11-15
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pubmed:meshHeading |
pubmed-meshheading:1987901-Carrier State,
pubmed-meshheading:1987901-Clinical Enzyme Tests,
pubmed-meshheading:1987901-Humans,
pubmed-meshheading:1987901-L-Lactate Dehydrogenase,
pubmed-meshheading:1987901-Leukemia-Lymphoma, Adult T-Cell,
pubmed-meshheading:1987901-Leukocyte Count,
pubmed-meshheading:1987901-Thymidine Kinase,
pubmed-meshheading:1987901-Tumor Markers, Biological
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pubmed:year |
1991
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pubmed:articleTitle |
[Serum deoxythymidine kinase activity in adult T-cell leukemia].
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pubmed:affiliation |
Dept. of 2nd Internal Medicine, Kumamoto University Medical School.
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pubmed:publicationType |
Journal Article,
English Abstract
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