Linked Life Data

19875937

Source:http://linkedlifedata.com/resource/pubmed/id/19875937

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
7
pubmed:dateCreated
2009-12-23
pubmed:abstractText
The generation of B cells is the result of several cell lineage choices, cell commitment and differentiation. These cellular transitions take place in a stepwise manner and are regulated at the transcriptional level. In recent years, investigators working in this field have made significant advances towards understanding the contribution of transcription factors during B lymphopoiesis.They have established the existence of transcription factor networks that are essential for the proper establishment and maintenance of the B cell lineage. As is the case for other developmental processes, emerging evidence demonstrates that B cell development is also regulated at the epigenetic level and that such regulation may act in concert with transcription factors. The aim of this review is to summarize the current knowledge concerning the epigenetic events that contribute toB lymphopoiesis.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Oct
pubmed:issn
1559-2308
pubmed:author
pubmed:issnType
Electronic
pubmed:day
1
pubmed:volume
4
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
462-8
pubmed:dateRevised
2010-8-6
pubmed:meshHeading
pubmed:year
2009
pubmed:articleTitle
Epigenetic events during B lymphocyte development.
pubmed:affiliation
Cellular Differentiation Group, Cancer Epigenetics and Biology Program, Bellvitge Biomedical Research Institute, Barcelona, Spain. mparra@idibell.cat
pubmed:publicationType
Journal Article, Review, Research Support, Non-U.S. Gov't