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rdf:type |
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|
lifeskim:mentions |
|
|
pubmed:issue |
8
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|
pubmed:dateCreated |
2009-10-30
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|
pubmed:abstractText |
Development of new (18)F-labeled tracers for positron emission tomography (PET) imaging is increasingly important. Herein, we described the synthesis of silicon analogues of [(18)F]fluoromisonidazole in order to develop new radiolabelled compounds for the detection of tumour hypoxic domain. Their stabilities and their in vivo biodistribution were evaluated.
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pubmed:language |
eng
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|
pubmed:journal |
|
|
pubmed:citationSubset |
IM
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|
pubmed:chemical |
|
|
pubmed:status |
MEDLINE
|
|
pubmed:month |
Nov
|
|
pubmed:issn |
1872-9614
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|
pubmed:author |
|
|
pubmed:issnType |
Electronic
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|
pubmed:volume |
36
|
|
pubmed:owner |
NLM
|
|
pubmed:authorsComplete |
Y
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|
pubmed:pagination |
895-905
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|
pubmed:meshHeading |
pubmed-meshheading:19875046-Animals,
pubmed-meshheading:19875046-Cell Line, Tumor,
pubmed-meshheading:19875046-Fibrosarcoma,
pubmed-meshheading:19875046-Fluorine Radioisotopes,
pubmed-meshheading:19875046-Isotope Labeling,
pubmed-meshheading:19875046-Male,
pubmed-meshheading:19875046-Metabolic Clearance Rate,
pubmed-meshheading:19875046-Mice,
pubmed-meshheading:19875046-Mice, Inbred C3H,
pubmed-meshheading:19875046-Misonidazole,
pubmed-meshheading:19875046-Organ Specificity,
pubmed-meshheading:19875046-Radiopharmaceuticals,
pubmed-meshheading:19875046-Silicon,
pubmed-meshheading:19875046-Tissue Distribution
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|
pubmed:year |
2009
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|
pubmed:articleTitle |
Design of silicon-based misonidazole analogues and (18)F-radiolabelling.
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|
pubmed:affiliation |
Department of Nuclear Medicine, Henri Becquerel Center and Rouen University Hospital and QuantIF- LITIS (EA4108), Rouen Cedex, France.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
|
