Linked Life Data

19871716

Source:http://linkedlifedata.com/resource/pubmed/id/19871716

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
4
pubmed:dateCreated
2010-6-23
pubmed:abstractText
The relationship between hemagglutination and hemolysis by the mumps virus has been studied under conditions which affect (a) the receptors of chicken red cells and (b) the adsorption and subsequent elution of the virus from these cells. The results show that the hemolytic action of the virus appears to involve some of the same receptor areas of erythrocytes that are implicated in hemagglutination. Materials such as allantoic fluid, egg white, and red cell extract, which inhibit the agglutination of chicken red cells by mumps virus, also interfere with its hemolytic activity. Of these inhibitors, egg white and red cell extract, which are readily destroyed by the virus during incubation at 37 degrees C., exert a greater antagonistic effect on hemagglutination than on hemolysis. Heated mumps virus or unheated influenza virus interferes with the hemolysis of red cells by untreated mumps virus. Though hemolysis takes place during elution of the virus after its adsorption on the red cell, the processes are apparently distinct. The hemolytic activity is easily affected by certain conditions of pH and temperature which have no effect on the ability of mumps virus to adsorb on and elute from red cells.
pubmed:commentsCorrections
pubmed:language
eng
pubmed:journal
pubmed:status
PubMed-not-MEDLINE
pubmed:month
Mar
pubmed:issn
0022-1007
pubmed:author
pubmed:issnType
Print
pubmed:day
31
pubmed:volume
91
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
403-16
pubmed:dateRevised
2010-9-28
pubmed:year
1950
pubmed:articleTitle
STUDIES OF THE HEMOLYSIS OF RED BLOOD CELLS BY MUMPS VIRUS : II. THE RELATIONSHIPS OF HEMAGGLUTINATION, VIRUS ELUTION, AND HEMOLYSIS.
pubmed:affiliation
Department of Epidemiology, School of Public Health, University of Michigan, Ann Arbor.
pubmed:publicationType
Journal Article