Linked Life Data

19870616

Source:http://linkedlifedata.com/resource/pubmed/id/19870616

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
4
pubmed:dateCreated
2010-6-23
pubmed:abstractText
The glomerulonephritis induced in rats by nephrotoxin was characterized clinically during its initial phase by severe albuminuria, cylindruria, and anasarca, but not by hematuria. Rapidly fatal nephritis was produced by injecting relatively large amounts of anti-kidney serum at frequent intervals. In such cases the blood urea mounted rapidly; the urea clearance fell; and death occurred within about 2 weeks. A milder nephritis of the chronic type was induced by giving smaller quantities of anti-kidney serum in either single or divided doses. In these instances there was no immediate alteration of the urea clearance. Lipemia and plasma protein deficit appeared with the development of anasarca. The majority of rats which survived the initial stage of this experimental nephritis continued to show marked albuminuria with casts until they died or were sacrificed months later. Some of these animals showed retardation of growth and a progressive fall of the urea clearance. Terminally there developed marked retention of urea, plasma protein deficit, anemia, and hypertension.
pubmed:commentsCorrections
pubmed:language
eng
pubmed:journal
pubmed:status
PubMed-not-MEDLINE
pubmed:month
Mar
pubmed:issn
0022-1007
pubmed:author
pubmed:issnType
Print
pubmed:day
31
pubmed:volume
65
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
527-40
pubmed:dateRevised
2010-9-27
pubmed:year
1937
pubmed:articleTitle
EXPERIMENTAL NEPHRITIS IN RATS INDUCED BY INJECTION OF ANTI-KIDNEY SERUM : II. CLINICAL AND FUNCTIONAL STUDIES.
pubmed:affiliation
Hospital of The Rockefeller Institute for Medical Research.
pubmed:publicationType
Journal Article