Linked Life Data

19870443

Source:http://linkedlifedata.com/resource/pubmed/id/19870443

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
5
pubmed:dateCreated
2010-6-23
pubmed:abstractText
1. A quantitative theory of the precipitin reaction based on the laws of classical chemistry has now been found applicable to the crystalline egg albumin-antibody system. Equations derived from the theory permit the calculation of the behavior of an anti-egg albumin serum over most of the reaction range after a few quantitative analyses have been made for the nitrogen precipitated. Data of other workers also conform to the proposed equations. 2. The empirical relation, shown to have advantages in the dye antidye system, may also be used for the Ea-A reaction. 3. Serum from the same animal after successive courses exhibits progressive changes which have been described graphically and quantitatively. These changes are believed to consist in the formation of more and more antibody capable of reacting with a larger number of chemically different groupings in the antigen molecule. 4. Evidence is presented that anti-egg albumin is not homogeneous, and that even after prolonged immunization the antiserum contains much low-grade antibody, incapable of forming precipitates unless more reactive precipitin is present. 5. Factors affecting the equivalence point ratio are discussed.
pubmed:commentsCorrections
pubmed:language
eng
pubmed:journal
pubmed:status
PubMed-not-MEDLINE
pubmed:month
Oct
pubmed:issn
0022-1007
pubmed:author
pubmed:issnType
Print
pubmed:day
31
pubmed:volume
62
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
697-720
pubmed:dateRevised
2010-9-28
pubmed:year
1935
pubmed:articleTitle
A QUANTITATIVE THEORY OF THE PRECIPITIN REACTION : III. THE REACTION BETWEEN CRYSTALLINE EGG ALBUMIN AND ITS HOMOLOGOUS ANTIBODY.
pubmed:affiliation
Department of Medicine, College of Physicians and Surgeons, Columbia University, and the Presbyterian Hospital, New York.
pubmed:publicationType
Journal Article