Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
5
pubmed:dateCreated
2010-6-23
pubmed:abstractText
1. The thermal death time of Trefonema pallidumin extracts from lesions in rabbits' testes was determined in vitro at fever temperatures using the Zinsser-Hopkins and Nichols strains. 2. The criteria to determine the persistence of infectivity of the heated extract were the following: the development of lesions on inoculation into rabbits, dark-field examination of tissue from the lesions, the outcome of blood Wassermann tests, and of reinoculation tests. 3. The thermal death time of the two strains of spirochetes was approximately the same, although the Nichols strain was somewhat the more resistant. In the case of the latter 5 hours at 39 degrees C., 3 hours at 40 degrees C., 2 hours at 41 degrees C., and 1 hour at 41.5 degrees C., were required to render infective extracts innocuous to other rabbits. 4. The thermal death time of T. pallidum in testicular extracts in vitro at fever temperatures is so short as to suggest that induced fever may be useful therapeutically in human syphilis.
pubmed:commentsCorrections
pubmed:language
eng
pubmed:journal
pubmed:status
PubMed-not-MEDLINE
pubmed:month
Oct
pubmed:issn
0022-1007
pubmed:author
pubmed:issnType
Print
pubmed:day
31
pubmed:volume
56
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
741-50
pubmed:dateRevised
2010-9-28
pubmed:year
1932
pubmed:articleTitle
STUDIES ON THE PHYSIOLOGICAL EFFECTS OF FEVER TEMPERATURES : III. THE THERMAL DEATH TIME OF TREPONEMA PALLIDUM IN VITRO WITH SPECIAL REFERENCE TO FEVER TEMPERATURES.
pubmed:affiliation
Department of Medicine, Division of Radiology of the University of Rochester School of Medicine and Dentistry, and Strong Memorial Hospital, Rochester, N. Y.
pubmed:publicationType
Journal Article