Linked Life Data

19869401

Source:http://linkedlifedata.com/resource/pubmed/id/19869401

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1
pubmed:dateCreated
2010-6-22
pubmed:abstractText
The mechanism of the precipitin reaction between antipneumococcus sera and the type-specific soluble carbohydrate is investigated. The sensitivity of the reaction is found to be generally constant when expressed by the product of the concentrations of the two reacting substances. Precipitin index (P.I.) is defined as one-millionth of the reciprocal value of this product. See PDF for Structure Zonal phenomena and their bearing on the absolute concentration and the equivalent weight of the antibody are discussed. The greater tendency towards exhibition of a post-zone in Type III is connected with the lower acid equivalent of the homologous specific carbohydrate. The influence of the addition of normal serum and the influence of slight changes in pH are studied. The addition of normal serum as well as the increase in pH promote the pro-zone, whereas decrease in pH promotes the post-zone. The sensitivity of the reaction is accordingly influenced by the pH in different ways depending on the range of concentration. The precipitin index allows the recognition and elimination of zonal irregularities. Thus it offers a method for the standardization of pneumonia antibody.
pubmed:commentsCorrections
pubmed:language
eng
pubmed:journal
pubmed:status
PubMed-not-MEDLINE
pubmed:month
Jan
pubmed:issn
0022-1007
pubmed:author
pubmed:issnType
Print
pubmed:day
1
pubmed:volume
47
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
57-92
pubmed:dateRevised
2010-9-28
pubmed:year
1928
pubmed:articleTitle
THE PRECIPITIN REACTION OF ANTIPNEUMOCOCCUS SERA : I. THE PRECIPITIN INDEX.
pubmed:affiliation
Department of Bacteriology, New York University and Bellevue Medical College, New York.
pubmed:publicationType
Journal Article