Linked Life Data

19869011

Source:http://linkedlifedata.com/resource/pubmed/id/19869011

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
5
pubmed:dateCreated
2010-6-23
pubmed:abstractText
When pneumococci are grown repeatedly in broth containing immune serum or bile, they become less virulent and less type-specific. These changes are apparently due to the fact that under the conditions mentioned a number of organisms appear which have lost certain properties. These variant organisms form colonies differing in appearance from the colonies of the typical organisms, and cultures made from the atypical colonies are avirulent and are not type-specific, The degree of modification of the original culture is directly related to the relative number of organisms that have undergone variation. After prolonged growth in bile or homologous immune serum variation may have become manifest in all the bacteria of the cultures and the change is then irreversible. The significance of these findings as regards the epidemiology of pneumococcus infections is noted.
pubmed:commentsCorrections
pubmed:language
eng
pubmed:journal
pubmed:status
PubMed-not-MEDLINE
pubmed:month
Apr
pubmed:issn
0022-1007
pubmed:author
pubmed:issnType
Print
pubmed:day
30
pubmed:volume
41
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
587-600
pubmed:dateRevised
2010-9-28
pubmed:year
1925
pubmed:articleTitle
VARIATIONS IN SPECIFICITY AND VIRULENCE OF PNEUMOCOCCI DURING GROWTH IN VITRO.
pubmed:affiliation
Hospital of The Rockefeller Institute for Medical Research.
pubmed:publicationType
Journal Article