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rdf:type |
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lifeskim:mentions |
umls-concept:C0001807,
umls-concept:C0035647,
umls-concept:C0085862,
umls-concept:C0205210,
umls-concept:C0449234,
umls-concept:C0597297,
umls-concept:C1299583,
umls-concept:C1332737,
umls-concept:C1425999,
umls-concept:C1514559,
umls-concept:C1549571,
umls-concept:C1608386,
umls-concept:C2239176
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pubmed:issue |
3
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pubmed:dateCreated |
2010-2-12
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pubmed:abstractText |
Through data mining the Stanford Microarray Database, the CKS1B transcript was found to be frequently upregulated in hepatocellular carcinomas (HCCs) with low alpha-fetal protein (AFP) expression. Together with SKP2, CKS1B is known to implicate p27(Kip1) protein turnover promoting cell-cycle progression.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/CKS1B protein, human,
http://linkedlifedata.com/resource/pubmed/chemical/Carrier Proteins,
http://linkedlifedata.com/resource/pubmed/chemical/Cyclin-Dependent Kinase Inhibitor...,
http://linkedlifedata.com/resource/pubmed/chemical/Cyclin-Dependent Kinases,
http://linkedlifedata.com/resource/pubmed/chemical/RNA, Messenger,
http://linkedlifedata.com/resource/pubmed/chemical/RNA, Small Interfering,
http://linkedlifedata.com/resource/pubmed/chemical/S-Phase Kinase-Associated Proteins,
http://linkedlifedata.com/resource/pubmed/chemical/Tumor Markers, Biological,
http://linkedlifedata.com/resource/pubmed/chemical/alpha-Fetoproteins
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pubmed:status |
MEDLINE
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pubmed:month |
Mar
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pubmed:issn |
1534-4681
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pubmed:author |
pubmed-author:ChenHong-YawHY,
pubmed-author:ChenYi-JuYJ,
pubmed-author:HuangChi-Ying FCY,
pubmed-author:HuangChing-WenCW,
pubmed-author:HuangHsuan-YingHY,
pubmed-author:JuanChung-ChouCC,
pubmed-author:KerChen-GuoCG,
pubmed-author:LiChien-FengCF,
pubmed-author:LinChing-YihCY,
pubmed-author:LiuHui-WenHW,
pubmed-author:ShihDeng-FuhDF,
pubmed-author:ShiueYow-LingYL
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pubmed:issnType |
Electronic
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pubmed:volume |
17
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
907-22
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pubmed:meshHeading |
pubmed-meshheading:19866239-Adult,
pubmed-meshheading:19866239-Aged,
pubmed-meshheading:19866239-Aged, 80 and over,
pubmed-meshheading:19866239-Blotting, Western,
pubmed-meshheading:19866239-Carcinoma, Hepatocellular,
pubmed-meshheading:19866239-Carrier Proteins,
pubmed-meshheading:19866239-Cyclin-Dependent Kinase Inhibitor p27,
pubmed-meshheading:19866239-Cyclin-Dependent Kinases,
pubmed-meshheading:19866239-Female,
pubmed-meshheading:19866239-Humans,
pubmed-meshheading:19866239-Immunoenzyme Techniques,
pubmed-meshheading:19866239-Liver Neoplasms,
pubmed-meshheading:19866239-Male,
pubmed-meshheading:19866239-Middle Aged,
pubmed-meshheading:19866239-Neoplasm Staging,
pubmed-meshheading:19866239-Prognosis,
pubmed-meshheading:19866239-RNA, Messenger,
pubmed-meshheading:19866239-RNA, Small Interfering,
pubmed-meshheading:19866239-Reverse Transcriptase Polymerase Chain Reaction,
pubmed-meshheading:19866239-S-Phase Kinase-Associated Proteins,
pubmed-meshheading:19866239-Tumor Cells, Cultured,
pubmed-meshheading:19866239-Tumor Markers, Biological,
pubmed-meshheading:19866239-alpha-Fetoproteins
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pubmed:year |
2010
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pubmed:articleTitle |
CKS1B overexpression implicates clinical aggressiveness of hepatocellular carcinomas but not p27(Kip1) protein turnover: an independent prognosticator with potential p27 (Kip1)-independent oncogenic attributes?
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pubmed:affiliation |
Department of Surgery, Yuan's General Hospital, Kaohsiung, Taiwan.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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