Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
23
pubmed:dateCreated
2009-11-5
pubmed:abstractText
A class of novel 2-aminobenzothiazoles have been identified as NPY Y(1) antagonists. Various N-heterocyclic substituted aminophenethyl-2-aminobenzothiazole analogs were synthesized to explore the SAR. Isothiourea analogs and ligands with high potency (K(i) 30 nM) have been identified.
pubmed:commentsCorrections
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Dec
pubmed:issn
1464-3405
pubmed:author
pubmed:issnType
Electronic
pubmed:day
1
pubmed:volume
19
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
6801-5
pubmed:dateRevised
2010-5-27
pubmed:meshHeading
pubmed:year
2009
pubmed:articleTitle
Discovery and SAR of cyclic isothioureas as novel NPY Y1 receptor antagonists.
pubmed:affiliation
Department of Medicinal Chemistry, Schering Plough Research Institute, Kenilworth, NJ 07033, USA. zhong-yue.sun@spcorp.com
pubmed:publicationType
Journal Article