Source:http://linkedlifedata.com/resource/pubmed/id/19864133
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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
23
|
| pubmed:dateCreated |
2009-11-5
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| pubmed:abstractText |
2-Amino-5-aryl-pyridines, exemplified by compound 1, had been identified as a synthetically tractable series of CB(2) agonists from a high-throughput screen of the GlaxoSmithKline compound collection. Described herein are the results of an investigation of the structure-activity relationships (SAR) which led to the identification a number of potent and selective agonists.
|
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
IM
|
| pubmed:chemical | |
| pubmed:status |
MEDLINE
|
| pubmed:month |
Dec
|
| pubmed:issn |
1464-3405
|
| pubmed:author |
pubmed-author:BeswickPaul JPJ,
pubmed-author:BrownAndrew JAJ,
pubmed-author:GiblinGerard M PGM,
pubmed-author:GleaveRobert JRJ,
pubmed-author:HaslamCarl PCP,
pubmed-author:LivermoreDavidD,
pubmed-author:MosesAndrewA,
pubmed-author:NicholsonNeville HNH,
pubmed-author:PageLee WLW,
pubmed-author:SlingsbyBrianB,
pubmed-author:SwarbrickMartin EME
|
| pubmed:issnType |
Electronic
|
| pubmed:day |
1
|
| pubmed:volume |
19
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
6578-81
|
| pubmed:meshHeading | |
| pubmed:year |
2009
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| pubmed:articleTitle |
2-Amino-5-aryl-pyridines as selective CB2 agonists: synthesis and investigation of structure-activity relationships.
|
| pubmed:affiliation |
Pain and Neuroexcitability Discovery Performance Unit, Neurosciences Centre of Excellence for Drug Discovery, GlaxoSmithKline, New Frontiers Science Park, Harlow, Essex CM19 5AW, United Kingdom. robert.j.gleave@gsk.com
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| pubmed:publicationType |
Journal Article
|