Source:http://linkedlifedata.com/resource/pubmed/id/19864031
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
2
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pubmed:dateCreated |
2010-12-7
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pubmed:abstractText |
The gap junction protein, connexin 43 (Cx43) might be involved in the development of atherosclerosis. However, little is known about Cx43 expression in human arteries. We histologically analyzed the distal portions of radial (RA) and internal thoracic arteries (ITAs) obtained from 29 patients undergoing coronary artery bypass graft surgery. The medial smooth muscle cells of RA expressed Cx43, the intensity of which correlated with nuclear factor kappa B (NF?B) activation. In contrast, the expression of Cx43 in ITA did not correlate with NF?B activation. Cx43 appears to be involved in the pathogenesis of atherosclerosis especially in muscular arteries.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Nov
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pubmed:issn |
1874-1754
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pubmed:author | |
pubmed:copyrightInfo |
Copyright © 2009 Elsevier Ireland Ltd. All rights reserved.
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pubmed:issnType |
Electronic
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pubmed:day |
19
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pubmed:volume |
145
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
270-2
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pubmed:meshHeading |
pubmed-meshheading:19864031-Aged,
pubmed-meshheading:19864031-Connexin 43,
pubmed-meshheading:19864031-Coronary Artery Disease,
pubmed-meshheading:19864031-Female,
pubmed-meshheading:19864031-Gene Expression Regulation,
pubmed-meshheading:19864031-Humans,
pubmed-meshheading:19864031-Male,
pubmed-meshheading:19864031-Middle Aged,
pubmed-meshheading:19864031-Radial Artery
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pubmed:year |
2010
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pubmed:articleTitle |
Connexin 43 expression is associated with vascular activation in human radial artery.
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pubmed:publicationType |
Letter,
Comparative Study
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