Linked Life Data

19863011

Source:http://linkedlifedata.com/resource/pubmed/id/19863011

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
9-10
pubmed:dateCreated
2009-10-29
pubmed:abstractText
Perosomus elumbis is a rare congenital anomaly of unknown aetiology characterized by the aplasia of the lumbosacral spinal cord and vertebrae, mostly associated with multiple other malformations of the hind limbs and the urogenital and intestinal tract. This report describes a stillborn female German Holstein calf showing a complete aplasia of the lumbosacrococcygeal portion of the spinal cord and vertebral column. In addition, both hind-limbs exhibited arthrogryposis and the musculature was completely replaced by adipose tissue. Furthermore, atresia ani and recti, agenesis of one kidney, one adrenal gland, and a hypoplastic and atretic female genital tract were detected. The aplasia of the lumbosacrococcygeal spinal cord and vertebral column and the other associated malformations in the presented case of perosomus elumbis may be the consequence of a combined developmental disturbance of the caudal neural tube, notochord and paraxial and intermediary mesoderm. However, it remains unclear whether the underlying cause is due to an inherited defect or due to an unknown exogenous factor disturbing embryogenesis in a critical developmental period.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:issn
0005-9366
pubmed:author
pubmed:issnType
Print
pubmed:volume
122
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
386-90
pubmed:meshHeading
pubmed:articleTitle
Perosomus elumbis in a black and white German Holstein calf.
pubmed:affiliation
Institut für Tierzucht und Vererbungsforschung, Stiftung Tierärztliche Hochschule Hannover.
pubmed:publicationType
Journal Article, Case Reports