Source:http://linkedlifedata.com/resource/pubmed/id/19861398
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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:dateCreated |
2009-10-28
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| pubmed:abstractText |
Cardiac resynchronization therapy (CRT) is a treatment of proven efficacy for selected patients with heart failure and associated conduction disturbances. The increasing financial burden that healthcare systems face has increased the interest in cost-effectiveness and cost-utility estimates, focused on devices with defibrillation capabilities (CRT-D), with a high upfront cost, as well as on simpler devices providing only biventricular pacing (CRT-P). Available economic estimates are largely dependent on data source, assumptions, modelling technique, time horizon, and perspective, leading to some variability in cost-effectiveness and cost-utility estimates. As a whole, cost-effectiveness and cost-utility estimates of both CRT-P and CRT-D improve as the time horizon examined is lengthened and appear to be below US$50,000 per quality-adjusted life-year, a threshold value commonly adopted for coverage of healthcare interventions in the USA and quite comparable with similar thresholds used within Europe. Limited data are available on the comparative cost-effectiveness or cost-utility of CRT-P and CRT-D devices. Moreover, more data on the effectiveness and long-term benefits of CRT-D and CRT-P are needed in order to estimate better the value of these treatments in the 'real world, as well as for attempts to improve cost-effectiveness through improved patient selection.
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| pubmed:language |
eng
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| pubmed:journal | |
| pubmed:citationSubset |
IM
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| pubmed:status |
MEDLINE
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| pubmed:month |
Nov
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| pubmed:issn |
1532-2092
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| pubmed:author | |
| pubmed:issnType |
Electronic
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| pubmed:volume |
11 Suppl 5
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| pubmed:owner |
NLM
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| pubmed:authorsComplete |
Y
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| pubmed:pagination |
v93-7
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| pubmed:meshHeading |
pubmed-meshheading:19861398-Cost-Benefit Analysis,
pubmed-meshheading:19861398-Defibrillators,
pubmed-meshheading:19861398-Delivery of Health Care,
pubmed-meshheading:19861398-Europe,
pubmed-meshheading:19861398-Heart Failure,
pubmed-meshheading:19861398-Humans,
pubmed-meshheading:19861398-Pacemaker, Artificial,
pubmed-meshheading:19861398-Patient Selection,
pubmed-meshheading:19861398-Quality-Adjusted Life Years,
pubmed-meshheading:19861398-Treatment Outcome,
pubmed-meshheading:19861398-United States
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| pubmed:year |
2009
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| pubmed:articleTitle |
Is cardiac resynchronization therapy cost-effective?
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| pubmed:affiliation |
Institute of Cardiology, University of Bologna and Azienda Ospedaliera S. Orsola-Malpighi, Via Massarenti 9, 40138 Bologna, Italy. giuseppe.boriani@unibo.it
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| pubmed:publicationType |
Journal Article
|