Source:http://linkedlifedata.com/resource/pubmed/id/19857066
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
5
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pubmed:dateCreated |
2009-10-27
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pubmed:abstractText |
The aim of this study was to examine the effect of Chlorella vulgaris on glucose metabolism in rats fed a high fat diet. Sixty 6-week-old male Wistar rats were divided into two groups: normal diet group (N group) and high fat diet group (H group); then the rats in each group were further divided into three subgroups and fed either Chlorella-free diets or diets with 5% (C5) or 10% (C10) (wt/wt) Chlorella for 9 weeks. Serum leptin concentration was significantly lower in the NC10 and HC10 groups than in the N and H groups. The fasting glucose concentration and homeostasis model assessment of insulin resistance of the HC10 group were significantly lower than those of the H group. Glutamate transporter 4 protein expression was significantly higher in the HC10 group than the H group. In conclusion, 10% Chlorella intake was more effective for blood glucose regulation than 5% Chlorella intake in rats fed a high fat diet. Chlorella intake may prevent insulin resistance in Wistar rats fed a high fat diet.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/Blood Glucose,
http://linkedlifedata.com/resource/pubmed/chemical/Dietary Fats,
http://linkedlifedata.com/resource/pubmed/chemical/Glucose Transporter Type 4,
http://linkedlifedata.com/resource/pubmed/chemical/Hypoglycemic Agents,
http://linkedlifedata.com/resource/pubmed/chemical/Leptin,
http://linkedlifedata.com/resource/pubmed/chemical/SLC2A4 protein, human
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pubmed:status |
MEDLINE
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pubmed:month |
Oct
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pubmed:issn |
1557-7600
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pubmed:author | |
pubmed:issnType |
Electronic
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pubmed:volume |
12
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1029-37
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pubmed:meshHeading |
pubmed-meshheading:19857066-Animals,
pubmed-meshheading:19857066-Blood Glucose,
pubmed-meshheading:19857066-Chlorella vulgaris,
pubmed-meshheading:19857066-Diet,
pubmed-meshheading:19857066-Dietary Fats,
pubmed-meshheading:19857066-Disease Models, Animal,
pubmed-meshheading:19857066-Glucose Transporter Type 4,
pubmed-meshheading:19857066-Hypoglycemic Agents,
pubmed-meshheading:19857066-Insulin Resistance,
pubmed-meshheading:19857066-Leptin,
pubmed-meshheading:19857066-Male,
pubmed-meshheading:19857066-Models, Animal,
pubmed-meshheading:19857066-Obesity,
pubmed-meshheading:19857066-Rats,
pubmed-meshheading:19857066-Rats, Wistar
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pubmed:year |
2009
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pubmed:articleTitle |
Effect of Chlorella vulgaris on glucose metabolism in Wistar rats fed high fat diet.
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pubmed:affiliation |
Department of Nutritional Science and Food Management, Ewha Womans University, Seoul, Republic of Korea.
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pubmed:publicationType |
Journal Article
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