| pubmed-article:19855953 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:19855953 | lifeskim:mentions | umls-concept:C0086418 | lld:lifeskim |
| pubmed-article:19855953 | lifeskim:mentions | umls-concept:C0030281 | lld:lifeskim |
| pubmed-article:19855953 | lifeskim:mentions | umls-concept:C0023789 | lld:lifeskim |
| pubmed-article:19855953 | lifeskim:mentions | umls-concept:C0750572 | lld:lifeskim |
| pubmed-article:19855953 | lifeskim:mentions | umls-concept:C0243127 | lld:lifeskim |
| pubmed-article:19855953 | lifeskim:mentions | umls-concept:C0024934 | lld:lifeskim |
| pubmed-article:19855953 | lifeskim:mentions | umls-concept:C0205251 | lld:lifeskim |
| pubmed-article:19855953 | lifeskim:mentions | umls-concept:C0443331 | lld:lifeskim |
| pubmed-article:19855953 | pubmed:issue | 2 | lld:pubmed |
| pubmed-article:19855953 | pubmed:dateCreated | 2010-1-21 | lld:pubmed |
| pubmed-article:19855953 | pubmed:abstractText | Defects in pancreatic beta cell turnover are implicated in the pathogenesis of type 2 diabetes by genetic markers for diabetes. Decreased beta cell neogenesis could contribute to diabetes. The longevity and turnover of human beta cells is unknown; in rodents <1 year old, a half-life of 30 days is estimated. Intracellular lipofuscin body (LB) accumulation is a hallmark of ageing in neurons. To estimate the lifespan of human beta cells, we measured beta cell LB accumulation in individuals aged 1-81 years. | lld:pubmed |
| pubmed-article:19855953 | pubmed:grant | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:19855953 | pubmed:grant | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:19855953 | pubmed:language | eng | lld:pubmed |
| pubmed-article:19855953 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:19855953 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:19855953 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:19855953 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:19855953 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:19855953 | pubmed:month | Feb | lld:pubmed |
| pubmed-article:19855953 | pubmed:issn | 1432-0428 | lld:pubmed |
| pubmed-article:19855953 | pubmed:author | pubmed-author:MorrisJ FJF | lld:pubmed |
| pubmed-article:19855953 | pubmed:author | pubmed-author:ClarkAA | lld:pubmed |
| pubmed-article:19855953 | pubmed:author | pubmed-author:HansenB CBC | lld:pubmed |
| pubmed-article:19855953 | pubmed:author | pubmed-author:HughesS JSJ | lld:pubmed |
| pubmed-article:19855953 | pubmed:author | pubmed-author:Pipeleers-Mar... | lld:pubmed |
| pubmed-article:19855953 | pubmed:author | pubmed-author:CnopMM | lld:pubmed |
| pubmed-article:19855953 | pubmed:author | pubmed-author:de KoningE... | lld:pubmed |
| pubmed-article:19855953 | pubmed:author | pubmed-author:JohnsonP R... | lld:pubmed |
| pubmed-article:19855953 | pubmed:author | pubmed-author:Igoillo-Estev... | lld:pubmed |
| pubmed-article:19855953 | pubmed:author | pubmed-author:HoppaM BMB | lld:pubmed |
| pubmed-article:19855953 | pubmed:author | pubmed-author:SayyedFF | lld:pubmed |
| pubmed-article:19855953 | pubmed:author | pubmed-author:van de LaarLL | lld:pubmed |
| pubmed-article:19855953 | pubmed:author | pubmed-author:GunterJ HJH | lld:pubmed |
| pubmed-article:19855953 | pubmed:author | pubmed-author:WallsG VGV | lld:pubmed |
| pubmed-article:19855953 | pubmed:author | pubmed-author:GrayD W GDW | lld:pubmed |
| pubmed-article:19855953 | pubmed:author | pubmed-author:CnopII | lld:pubmed |
| pubmed-article:19855953 | pubmed:issnType | Electronic | lld:pubmed |
| pubmed-article:19855953 | pubmed:volume | 53 | lld:pubmed |
| pubmed-article:19855953 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:19855953 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:19855953 | pubmed:pagination | 321-30 | lld:pubmed |
| pubmed-article:19855953 | pubmed:meshHeading | pubmed-meshheading:19855953... | lld:pubmed |
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| pubmed-article:19855953 | pubmed:meshHeading | pubmed-meshheading:19855953... | lld:pubmed |
| pubmed-article:19855953 | pubmed:meshHeading | pubmed-meshheading:19855953... | lld:pubmed |
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| pubmed-article:19855953 | pubmed:meshHeading | pubmed-meshheading:19855953... | lld:pubmed |
| pubmed-article:19855953 | pubmed:year | 2010 | lld:pubmed |
| pubmed-article:19855953 | pubmed:articleTitle | The long lifespan and low turnover of human islet beta cells estimated by mathematical modelling of lipofuscin accumulation. | lld:pubmed |
| pubmed-article:19855953 | pubmed:affiliation | Laboratory of Experimental Medicine and Division of Endocrinology, Université Libre de Bruxelles, Brussels, Belgium. | lld:pubmed |
| pubmed-article:19855953 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:19855953 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
| pubmed-article:19855953 | pubmed:publicationType | Research Support, N.I.H., Extramural | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:19855953 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:19855953 | lld:pubmed |
