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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
18
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pubmed:dateCreated |
2009-11-12
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pubmed:abstractText |
Toll-like receptors (TLRs) are innate immune sensors that are integral to resisting chronic and opportunistic infections. Mounting evidence implicates TLR polymorphisms in susceptibilities to various infectious diseases, including HIV-1. We investigated the impact of TLR single nucleotide polymorphisms (SNPs) on clinical outcome in a seroincident cohort of HIV-1-infected volunteers.
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pubmed:grant |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
|
|
pubmed:status |
MEDLINE
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pubmed:month |
Nov
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|
pubmed:issn |
1473-5571
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pubmed:author |
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pubmed:issnType |
Electronic
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pubmed:day |
27
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pubmed:volume |
23
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
2387-95
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pubmed:dateRevised |
2011-2-14
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pubmed:meshHeading |
pubmed-meshheading:19855253-Adult,
pubmed-meshheading:19855253-Algorithms,
pubmed-meshheading:19855253-CD4 Lymphocyte Count,
pubmed-meshheading:19855253-Cohort Studies,
pubmed-meshheading:19855253-Female,
pubmed-meshheading:19855253-Genetic Predisposition to Disease,
pubmed-meshheading:19855253-Genotype,
pubmed-meshheading:19855253-HIV Infections,
pubmed-meshheading:19855253-HIV-1,
pubmed-meshheading:19855253-Humans,
pubmed-meshheading:19855253-Linkage Disequilibrium,
pubmed-meshheading:19855253-Male,
pubmed-meshheading:19855253-Polymorphism, Genetic,
pubmed-meshheading:19855253-Toll-Like Receptor 2,
pubmed-meshheading:19855253-Toll-Like Receptor 3,
pubmed-meshheading:19855253-Toll-Like Receptor 4,
pubmed-meshheading:19855253-Toll-Like Receptor 9,
pubmed-meshheading:19855253-Viral Load
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pubmed:year |
2009
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pubmed:articleTitle |
Polymorphisms in toll-like receptor 4 and toll-like receptor 9 influence viral load in a seroincident cohort of HIV-1-infected individuals.
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pubmed:affiliation |
Program in Pathobiology, Department of Global Health, University of Washington, Seattle, Washington, USA.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't,
Research Support, N.I.H., Extramural
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