Linked Life Data

19855177

Source:http://linkedlifedata.com/resource/pubmed/id/19855177

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
22
pubmed:dateCreated
2009-11-10
pubmed:abstractText
Higher order chromosome structures are the hallmark of mitotic and meiotic cells. Chromatin condensation and compaction are essential for rapid chromosome congression and accurate chromosome segregation during cell division. The core histones possess tails at their amino-termini. These tails, which extend from the surface of the nucleosomes, are highly dynamic and subject to an extensive array of covalent modifications. Modified histone tails play an important role, not only in the folding of nucleosomal arrays into higher order chromatin structures but also in gene regulation. The combination of these distinct covalent modifications of histones constitutes "the histone code" that regulates various cellular processes, including mitotic and meiotic progression.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Nov
pubmed:issn
1551-4005
pubmed:author
pubmed:issnType
Electronic
pubmed:day
15
pubmed:volume
8
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
3688-94
pubmed:meshHeading
pubmed:year
2009
pubmed:articleTitle
Covalent modifications of histones during mitosis and meiosis.
pubmed:affiliation
Department of Environmental Medicine, New York University Langone Medical Center, Tuxedo, NY, USA.
pubmed:publicationType
Journal Article, Review