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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
3
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pubmed:dateCreated |
2010-3-2
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pubmed:abstractText |
The aberrant expression of histone-modifying enzymes such as histone deacetylases contributes to oncogenesis. It is unclear whether RBP2, a newly identified histone demethylase, is involved in cancer development/progression. We determined RBP2 expression in gastric cancer and its biologic function in cancer cells.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
AIM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/CDKN1A protein, human,
http://linkedlifedata.com/resource/pubmed/chemical/CDKN1B protein, human,
http://linkedlifedata.com/resource/pubmed/chemical/Cyclin-Dependent Kinase Inhibitor...,
http://linkedlifedata.com/resource/pubmed/chemical/Cyclin-Dependent Kinase Inhibitor...,
http://linkedlifedata.com/resource/pubmed/chemical/Cyclin-Dependent Kinase Inhibitor...,
http://linkedlifedata.com/resource/pubmed/chemical/Histones,
http://linkedlifedata.com/resource/pubmed/chemical/Intracellular Signaling Peptides...,
http://linkedlifedata.com/resource/pubmed/chemical/RBP2 protein, human,
http://linkedlifedata.com/resource/pubmed/chemical/RNA, Messenger,
http://linkedlifedata.com/resource/pubmed/chemical/Retinol-Binding Proteins, Cellular
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pubmed:status |
MEDLINE
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pubmed:month |
Mar
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pubmed:issn |
1528-0012
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pubmed:author |
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pubmed:copyrightInfo |
Copyright 2010 AGA Institute. Published by Elsevier Inc. All rights reserved.
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pubmed:issnType |
Electronic
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pubmed:volume |
138
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
981-92
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pubmed:dateRevised |
2011-11-17
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pubmed:meshHeading |
pubmed-meshheading:19850045-Adult,
pubmed-meshheading:19850045-Aged,
pubmed-meshheading:19850045-Blotting, Western,
pubmed-meshheading:19850045-Cell Aging,
pubmed-meshheading:19850045-Cyclin-Dependent Kinase Inhibitor p16,
pubmed-meshheading:19850045-Cyclin-Dependent Kinase Inhibitor p21,
pubmed-meshheading:19850045-Cyclin-Dependent Kinase Inhibitor p27,
pubmed-meshheading:19850045-Female,
pubmed-meshheading:19850045-Gene Expression Regulation, Enzymologic,
pubmed-meshheading:19850045-Gene Expression Regulation, Neoplastic,
pubmed-meshheading:19850045-HeLa Cells,
pubmed-meshheading:19850045-Histones,
pubmed-meshheading:19850045-Humans,
pubmed-meshheading:19850045-Immunohistochemistry,
pubmed-meshheading:19850045-Intracellular Signaling Peptides and Proteins,
pubmed-meshheading:19850045-Male,
pubmed-meshheading:19850045-Methylation,
pubmed-meshheading:19850045-Middle Aged,
pubmed-meshheading:19850045-Promoter Regions, Genetic,
pubmed-meshheading:19850045-RNA, Messenger,
pubmed-meshheading:19850045-RNA Interference,
pubmed-meshheading:19850045-Retinol-Binding Proteins, Cellular,
pubmed-meshheading:19850045-Reverse Transcriptase Polymerase Chain Reaction,
pubmed-meshheading:19850045-Stomach Neoplasms,
pubmed-meshheading:19850045-Up-Regulation
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pubmed:year |
2010
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pubmed:articleTitle |
The histone demethylase RBP2 Is overexpressed in gastric cancer and its inhibition triggers senescence of cancer cells.
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pubmed:affiliation |
Department of Medicine, Division of Hematology, Karolinska University Hospital Solna and Karolinska Institutet, SE-171 76 Stockholm, Sweden.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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