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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
4
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pubmed:dateCreated |
2009-10-22
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pubmed:abstractText |
Endothelin-1 (ET-1) has been implicated in the pathophysiology of cerebral vasospasm. Chloride (Cl-) channels exist in vascular smooth muscle and activation of these channels leads to depolarization and contraction. The aim of the present study was to test the effect of 5-nitro-2-(3-phenylpropylamino)-benzoate (NPPB), a Cl- channel antagonist, on the ET-1-induced cerebral vasospasm in rabbit basilar artery and thus investigate the contribution of Cl- channels.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Oct
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pubmed:issn |
1019-5149
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pubmed:author |
pubmed-author:BarunSureyyaS,
pubmed-author:BaykanerM KemalMK,
pubmed-author:BelenHayrunnisa BolayHB,
pubmed-author:DoguluFikretF,
pubmed-author:ElmasCigdemC,
pubmed-author:EmmezHakanH,
pubmed-author:ErcanSevimS,
pubmed-author:ErdoganDenizD,
pubmed-author:IlgitErhanE,
pubmed-author:KurtGokhanG,
pubmed-author:OnalBaranB,
pubmed-author:SariogluYusufY
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pubmed:issnType |
Print
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pubmed:volume |
19
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
380-6
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pubmed:meshHeading |
pubmed-meshheading:19847759-Angiogenesis Inhibitors,
pubmed-meshheading:19847759-Animals,
pubmed-meshheading:19847759-Basilar Artery,
pubmed-meshheading:19847759-Cerebral Angiography,
pubmed-meshheading:19847759-Chloride Channels,
pubmed-meshheading:19847759-Endothelin-1,
pubmed-meshheading:19847759-Female,
pubmed-meshheading:19847759-Male,
pubmed-meshheading:19847759-Microscopy, Electron, Transmission,
pubmed-meshheading:19847759-Muscle, Smooth, Vascular,
pubmed-meshheading:19847759-Neurons,
pubmed-meshheading:19847759-Nitrobenzoates,
pubmed-meshheading:19847759-Rabbits,
pubmed-meshheading:19847759-Vasoconstriction,
pubmed-meshheading:19847759-Vasospasm, Intracranial
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pubmed:year |
2009
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pubmed:articleTitle |
Effect of a chloride channel inhibitor, 5-nitro-2- (3-phenylpropylamino)-benzoate, on endothelin-1 induced vasoconstriction in rabbit basilar artery.
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pubmed:affiliation |
Gazi University, Neurosurgery Department, Ankara, Turkey. alpob@yahoo.com
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pubmed:publicationType |
Journal Article
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