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rdf:type |
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|
lifeskim:mentions |
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pubmed:issue |
10
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pubmed:dateCreated |
2009-10-22
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pubmed:abstractText |
Cancer cells become refractory to chemotherapy as a consequence of their overexpressing ABC transporters that extrude not only the therapeutic agent but other unrelated compounds such as chemotoxins and biocides before they can reach their intended targets. A compound that can inhibit the activity of these transporters may find use as an adjunct to chemotherapy that had been rendered ineffective.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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|
pubmed:status |
MEDLINE
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pubmed:month |
Oct
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pubmed:issn |
1791-7530
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pubmed:author |
pubmed-author:AmaralLeonardL,
pubmed-author:DuarteNoéliaN,
pubmed-author:FerreiraMaria-José UMJ,
pubmed-author:MartinsAnaA,
pubmed-author:MartinsMartaM,
pubmed-author:MolnárJosephJ,
pubmed-author:MulhovoSilvaS,
pubmed-author:RamalheteCátiaC,
pubmed-author:SerlyJuliannaJ,
pubmed-author:SpenglerGabriellaG,
pubmed-author:ViveirosMiguelM
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pubmed:issnType |
Electronic
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pubmed:volume |
29
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pubmed:owner |
NLM
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|
pubmed:authorsComplete |
Y
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pubmed:pagination |
3989-93
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pubmed:meshHeading |
pubmed-meshheading:19846941-Animals,
pubmed-meshheading:19846941-Cell Line, Tumor,
pubmed-meshheading:19846941-Flow Cytometry,
pubmed-meshheading:19846941-Fluorometry,
pubmed-meshheading:19846941-Glycosides,
pubmed-meshheading:19846941-Lymphoma, T-Cell,
pubmed-meshheading:19846941-Mice,
pubmed-meshheading:19846941-Momordica,
pubmed-meshheading:19846941-P-Glycoprotein,
pubmed-meshheading:19846941-Terpenes,
pubmed-meshheading:19846941-Transfection,
pubmed-meshheading:19846941-Triterpenes
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pubmed:year |
2009
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pubmed:articleTitle |
Evaluation of cucurbitane-type triterpenoids from Momordica balsamina on P-glycoprotein (ABCB1) by flow cytometry and real-time fluorometry.
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pubmed:affiliation |
Unit of Mycobacteriology, Instituto de Higiene e Medicina Tropical, Universidade Nova de Lisboa, Rua da Junqueira 96, 1349-008 Lisboa, Portugal.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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