Linked Life Data

19845074

Source:http://linkedlifedata.com/resource/pubmed/id/19845074

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pubmed-article:19845074pubmed:abstractTextThe majority of hypertensive patients require combination therapy to achieve BP goals. Guidelines recommend dual therapy in newly diagnosed patients with BP > 160/100mm Hg. Calcium channel blocker (CCB)/ACE inhibitor and beta-blocker (beta-adrenoceptor antagonists)/diuretic combinations are among regimens considered effective for BP control. ACE inhibitors, beta-blockers, and CCBs are recommended for use in patients after myocardial infarction (MI). Statistical modeling from INVEST (INternational VErapamil-Trandolapril STudy), suggests an association between dual and triple therapy and decreased risk of primary outcome ([PO] first occurrence of death, nonfatal MI, or nonfatal stroke) in patients with hypertension and coronary artery disease (CAD).lld:pubmed
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pubmed-article:19845074pubmed:articleTitleDual therapy in hypertensive patients with coronary artery disease: the role of calcium channel blockers and beta-blockers.lld:pubmed
pubmed-article:19845074pubmed:affiliationUniversity of Chicago School of Medicine, Department of Medicine, Hypertensive Diseases Unit, Chicago, Illinois 60637, USA. gbakris@earthlink.netlld:pubmed
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