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rdf:type |
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lifeskim:mentions |
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pubmed:dateCreated |
2009-10-22
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pubmed:abstractText |
The majority of hypertensive patients require combination therapy to achieve BP goals. Guidelines recommend dual therapy in newly diagnosed patients with BP > 160/100mm Hg. Calcium channel blocker (CCB)/ACE inhibitor and beta-blocker (beta-adrenoceptor antagonists)/diuretic combinations are among regimens considered effective for BP control. ACE inhibitors, beta-blockers, and CCBs are recommended for use in patients after myocardial infarction (MI). Statistical modeling from INVEST (INternational VErapamil-Trandolapril STudy), suggests an association between dual and triple therapy and decreased risk of primary outcome ([PO] first occurrence of death, nonfatal MI, or nonfatal stroke) in patients with hypertension and coronary artery disease (CAD).
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:issn |
1175-3277
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
7 Suppl 1
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
25-9
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pubmed:meshHeading |
pubmed-meshheading:19845074-Adrenergic beta-Antagonists,
pubmed-meshheading:19845074-Aged,
pubmed-meshheading:19845074-Analysis of Variance,
pubmed-meshheading:19845074-Angiotensin-Converting Enzyme Inhibitors,
pubmed-meshheading:19845074-Antihypertensive Agents,
pubmed-meshheading:19845074-Atenolol,
pubmed-meshheading:19845074-Blood Pressure,
pubmed-meshheading:19845074-Calcium Channel Blockers,
pubmed-meshheading:19845074-Coronary Artery Disease,
pubmed-meshheading:19845074-Diuretics,
pubmed-meshheading:19845074-Drug Therapy, Combination,
pubmed-meshheading:19845074-Female,
pubmed-meshheading:19845074-Humans,
pubmed-meshheading:19845074-Hydrochlorothiazide,
pubmed-meshheading:19845074-Hypertension,
pubmed-meshheading:19845074-Indoles,
pubmed-meshheading:19845074-Male,
pubmed-meshheading:19845074-Middle Aged,
pubmed-meshheading:19845074-Proportional Hazards Models,
pubmed-meshheading:19845074-Retrospective Studies,
pubmed-meshheading:19845074-Treatment Outcome,
pubmed-meshheading:19845074-Verapamil
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pubmed:year |
2007
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pubmed:articleTitle |
Dual therapy in hypertensive patients with coronary artery disease: the role of calcium channel blockers and beta-blockers.
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pubmed:affiliation |
University of Chicago School of Medicine, Department of Medicine, Hypertensive Diseases Unit, Chicago, Illinois 60637, USA. gbakris@earthlink.net
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pubmed:publicationType |
Journal Article,
Clinical Trial,
Randomized Controlled Trial
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