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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
5
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pubmed:dateCreated |
2009-10-21
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pubmed:abstractText |
Drugs with I(Kr)-blocking action cause secondary long-QT syndrome. Several cases have been associated with mutations of genes coding cardiac ion channels, but their frequency among patients affected by drug-induced long-QT syndrome (dLQTS) and the resultant molecular effects remain unknown.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Oct
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pubmed:issn |
1941-3084
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pubmed:author |
pubmed-author:AkaoMasaharuM,
pubmed-author:AshiharaTakashiT,
pubmed-author:DingWei-GuangWG,
pubmed-author:HarunaTetsuyaT,
pubmed-author:HayashiHidekiH,
pubmed-author:HigashiYukeiY,
pubmed-author:HorieMinoruM,
pubmed-author:ImotoKeijiK,
pubmed-author:IshidaKatsuyaK,
pubmed-author:ItoMakotoM,
pubmed-author:ItohHidekiH,
pubmed-author:JoHikariH,
pubmed-author:KawamuraMihokoM,
pubmed-author:KubotaTomokiT,
pubmed-author:MakiyamaTakeruT,
pubmed-author:MatsuuraHiroshiH,
pubmed-author:MiyamotoAkashiA,
pubmed-author:MoriChikaraC,
pubmed-author:NagaokaIoriI,
pubmed-author:NakazawaYukoY,
pubmed-author:NishioYukikoY,
pubmed-author:OhnoSeikoS,
pubmed-author:OkaYukoY,
pubmed-author:OkajimaKatsunoriK,
pubmed-author:SakaguchiTomokoT,
pubmed-author:SugimotoYoshihisaY,
pubmed-author:WatanabeEiichiE,
pubmed-author:WatanabeIchiroI,
pubmed-author:YaoTakenoriT,
pubmed-author:ZendaNaokoN
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pubmed:issnType |
Electronic
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pubmed:volume |
2
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
511-23
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pubmed:dateRevised |
2011-7-22
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pubmed:meshHeading |
pubmed-meshheading:19843919-Adult,
pubmed-meshheading:19843919-Aged,
pubmed-meshheading:19843919-Animals,
pubmed-meshheading:19843919-Computer Simulation,
pubmed-meshheading:19843919-Cricetinae,
pubmed-meshheading:19843919-DNA Mutational Analysis,
pubmed-meshheading:19843919-Ether-A-Go-Go Potassium Channels,
pubmed-meshheading:19843919-Female,
pubmed-meshheading:19843919-Genotype,
pubmed-meshheading:19843919-Humans,
pubmed-meshheading:19843919-Incidence,
pubmed-meshheading:19843919-Japan,
pubmed-meshheading:19843919-KCNQ1 Potassium Channel,
pubmed-meshheading:19843919-Long QT Syndrome,
pubmed-meshheading:19843919-Male,
pubmed-meshheading:19843919-Middle Aged,
pubmed-meshheading:19843919-Muscle Proteins,
pubmed-meshheading:19843919-Mutation, Missense,
pubmed-meshheading:19843919-Risk Factors,
pubmed-meshheading:19843919-Sodium Channels,
pubmed-meshheading:19843919-Transfection
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pubmed:year |
2009
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pubmed:articleTitle |
Latent genetic backgrounds and molecular pathogenesis in drug-induced long-QT syndrome.
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pubmed:affiliation |
Department of Cardiovascular and Respiratory Medicine, Shiga University of Medical Science, Shiga 520-2192, Japan.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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