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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
11
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pubmed:dateCreated |
2009-11-9
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pubmed:abstractText |
Genetic polymorphisms that influence serotonin (5-hydroxytryptamine, 5HT) neurotransmission are candidates for contributing to susceptibility to posttraumatic stress disorder (PTSD). The objective of our study was to determine if a variable length polymorphism for the promoter regions of the 5HT transporter (5HTTLPR), and/or a substitution polymorphism in the promoter region for the 5HT2A receptor, would be associated with PTSD in a trauma exposed population of adult African-Americans.
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pubmed:grant |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:issn |
1520-6394
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pubmed:author |
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pubmed:issnType |
Electronic
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pubmed:volume |
26
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
993-7
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pubmed:dateRevised |
2010-12-3
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pubmed:meshHeading |
pubmed-meshheading:19842167-Adult,
pubmed-meshheading:19842167-African Americans,
pubmed-meshheading:19842167-Alleles,
pubmed-meshheading:19842167-Case-Control Studies,
pubmed-meshheading:19842167-Comorbidity,
pubmed-meshheading:19842167-Depressive Disorder, Major,
pubmed-meshheading:19842167-Diagnostic and Statistical Manual of Mental Disorders,
pubmed-meshheading:19842167-Female,
pubmed-meshheading:19842167-Gene Expression,
pubmed-meshheading:19842167-Genetic Predisposition to Disease,
pubmed-meshheading:19842167-Genotype,
pubmed-meshheading:19842167-Humans,
pubmed-meshheading:19842167-Male,
pubmed-meshheading:19842167-Middle Aged,
pubmed-meshheading:19842167-Polymorphism, Genetic,
pubmed-meshheading:19842167-Receptors, Serotonin,
pubmed-meshheading:19842167-Serotonin Plasma Membrane Transport Proteins,
pubmed-meshheading:19842167-Stress Disorders, Post-Traumatic,
pubmed-meshheading:19842167-Young Adult
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pubmed:year |
2009
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pubmed:articleTitle |
Serotonin polymorphisms and posttraumatic stress disorder in a trauma exposed African American population.
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pubmed:affiliation |
Howard University College of Medicine, Department of Psychiatry, Washington, District of Columbia 20060, USA. TMellman@Howard.edu
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pubmed:publicationType |
Journal Article,
Research Support, N.I.H., Extramural
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